Academic Journal
Soluble ST2 as a Potential Biomarker in Pericardial Fluid of Coronary Artery Patients
| العنوان: | Soluble ST2 as a Potential Biomarker in Pericardial Fluid of Coronary Artery Patients |
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| المؤلفون: | Reşat Dikme, Mahmut Padak, Mesut Işık, İsmail Koyuncu, Ebru Temiz, Mehmet Salih Aydın, Ömer Göç |
| المصدر: | Brazilian Journal of Cardiovascular Surgery, Vol 36, Iss 5, Pp 677-684 (2021) |
| بيانات النشر: | Sociedade Brasileira de Cirurgia Cardiovascular, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Surgery LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | Coronary Artery Disease, Pericardial Fluid, Real-Time Polymerase Chain Reaction, IL1RL1 protein, human, Biomarkers, Prognosis, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Abstract Introduction: The growth Stimulation expressed gene 2 (ST2) (or interleukin 1 receptor-like 1, also known as IL1RL1) is considered a biomarker of poor prognosis in cardiovascular diseases. The aims of this study are to investigate ST2 in the pericardial fluid (PF) of coronary artery disease patients and to contribute to the understanding of the pathophysiology of coronary artery disease. Methods: 40 patients (blood plasma and PF) who underwent coronary artery bypass surgery and 40 controls (blood plasma only) were included in this study. Soluble ST2 (sST2) level was determined by enzyme-linked ımmunosorbent assay method in plasma and PF, and sST2 gene expression was determined by quantitative real-time polymerase chain reaction (QRT-PCR) method. Results: The sST2 level was found to be 44.89 ng/ml and 390.357 ng/ml in the control and patient groups’ plasma, and 223.992 ng/ml in the PF of the patient group. An increase in sST2 level was detected in the patient group compared to the control group (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-9741 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382021000500677&tlng=en; https://doaj.org/toc/1678-9741 |
| DOI: | 10.21470/1678-9741-2020-0317 |
| URL الوصول: | https://doaj.org/article/cd9cb7c5ec314b0fbd1bfaea3306e0f6 |
| رقم الانضمام: | edsdoj.9cb7c5ec314b0fbd1bfaea3306e0f6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16789741 |
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| DOI: | 10.21470/1678-9741-2020-0317 |