Academic Journal

Noninvasive right ventricular work in patients with atrial septal defects: a proof-of-concept study

التفاصيل البيبلوغرافية
العنوان: Noninvasive right ventricular work in patients with atrial septal defects: a proof-of-concept study
المؤلفون: Jian Wu, Xinyi Huang, Weibin Chen, Yiruo Tang, Xu Chen, Xinyu Wang, Bo Jing, Yuanyuan Sun, Kunhui Huang, Qiumei Gao, Xueming Liu, Maolong Su
المصدر: Cardiovascular Ultrasound, Vol 21, Iss 1, Pp 1-10 (2023)
بيانات النشر: BMC, 2023.
سنة النشر: 2023
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: Echocardiography, Right ventricular myocardial work, Atrial septal defect, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Abstract Background Noninvasive right ventricular (RV) myocardial work (RVMW) determined by echocardiography is a novel indicator used to estimate RV systolic function. To date, the feasibility of using RVMW has not been verified in assessing RV function in patients with atrial septal defect (ASD). Methods Noninvasive RVMW was analysed in 29 ASD patients (median age, 49 years; 21% male) and 29 age- and sex-matched individuals without cardiovascular disease. The ASD patients underwent echocardiography and right heart catheterization (RHC) within 24 h. Results The RV global work index (RVGWI), RV global constructive work (RVGCW), and RV global wasted work (RVGWW) were significantly higher in the ASD patients than in the controls, while there was no significant difference in RV global work efficiency (RVGWE). RV global longitudinal strain (RV GLS), RVGWI, RVGCW, and RVGWW demonstrated significant correlations with RHC-derived stroke volume (SV) and SV index. The RVGWI (area under receiver operating characteristic curve [AUC] = 0.895), RVGCW (AUC = 0.922), and RVGWW (AUC = 0.870) could be considered good predictors of ASD and were superior to RV GLS (AUC = 0.656). Conclusion The RVGWI, RVGCW, and RVGWW could be used to assess RV systolic function and are correlated with RHC-derived SV and SV index in patients with ASD. Graphical Abstract
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1476-7120
Relation: https://doaj.org/toc/1476-7120
DOI: 10.1186/s12947-023-00306-8
URL الوصول: https://doaj.org/article/9b765579d6d94576b2b4830ada379492
رقم الانضمام: edsdoj.9b765579d6d94576b2b4830ada379492
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14767120
DOI:10.1186/s12947-023-00306-8