التفاصيل البيبلوغرافية
| العنوان: |
Effect of the probiotic strain, Lactiplantibacillus plantarum P9, on chronic constipation: A randomized, double-blind, placebo-controlled study |
| المؤلفون: |
Teng Ma, Ni Yang, Yong Xie, Yingmeng Li, Qiuping Xiao, Qiong Li, Hao Jin, Longjin Zheng, Zhihong Sun, Kexuan Zuo, Lai-Yu Kwok, Heping Zhang, Nonghua Lu, Wenjun Liu |
| المصدر: |
Pharmacological Research, Vol 191, Iss , Pp 106755- (2023) |
| بيانات النشر: |
Elsevier, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Therapeutics. Pharmacology |
| مصطلحات موضوعية: |
Chronic constipation, Lactiplantibacillus plantarum P9, Multi-omics, Metagenomics, Fecal metabolome, Therapeutics. Pharmacology, RM1-950 |
| الوصف: |
Chronic constipation (CC) is a common gastrointestinal condition associated with intestinal inflammation, and the condition considerably impairs patients’ quality of life. We conducted a large-scale 42-day randomized, double-blind, placebo-controlled trial to investigate the effect of probiotics in alleviating CC. 163 patients diagnosed with CC (following Rome IV criteria) were randomly divided into probiotic (n = 78; received Lactiplantibacillus plantarum P9 [P9]; 1 ×1011 CFU/day) and placebo (n = 85; received placebo material) groups. Ingesting P9 significantly improved the weekly mean frequency of complete spontaneous bowel movements (CSBMs) and spontaneous bowel movements (SBMs), while significantly reducing the level of worries and concerns (WO; P |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1096-1186 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1043661823001111; https://doaj.org/toc/1096-1186 |
| DOI: |
10.1016/j.phrs.2023.106755 |
| URL الوصول: |
https://doaj.org/article/9ae121fd0b2744dcb4635d3a31dce94c |
| رقم الانضمام: |
edsdoj.9ae121fd0b2744dcb4635d3a31dce94c |
| قاعدة البيانات: |
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