التفاصيل البيبلوغرافية
| العنوان: |
Acute pleiotropic effects of dapagliflozin in type 2 diabetic patients with heart failure with reduced ejection fraction: a crossover trial |
| المؤلفون: |
Fahmida Ilyas, Lynette Jones, Su Ling Tee, Matthew Horsfall, Amy Swan, Fiona Wollaston, Tracy Hecker, Carla De Pasquale, Simeoni Thomas, William Chong, Steve Stranks, Arduino A. Mangoni, Joseph B. Selvanayagam, Derek P. Chew, Carmine G. De Pasquale |
| المصدر: |
ESC Heart Failure, Vol 8, Iss 5, Pp 4346-4352 (2021) |
| بيانات النشر: |
Wiley, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: |
HFrEF, Dapagliflozin, Mechanism, Acute effects, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: |
Abstract Aims This study aimed to explore the rapid effects of dapagliflozin in heart failure with reduced ejection fraction (HFrEF). Methods and results We studied the functional, echocardiographic, electrophysiological, lung ultrasound, ambulatory blood pressure (BP), microvascular and macrovascular function, and biochemical effects of 2 week treatment with dapagliflozin in 19 type 2 diabetic HFrEF patients in a double‐blind, crossover, placebo‐controlled trial. Dapagliflozin had no significant effect on clinical, functional, or quality of life parameters. Dapagliflozin reduced systolic BP [114 (105, 131) vs. 106 (98, 113) mmHg, P |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2055-5822 |
| Relation: |
https://doaj.org/toc/2055-5822 |
| DOI: |
10.1002/ehf2.13553 |
| URL الوصول: |
https://doaj.org/article/9aa33df196414a09b2353856e6d3b925 |
| رقم الانضمام: |
edsdoj.9aa33df196414a09b2353856e6d3b925 |
| قاعدة البيانات: |
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