Academic Journal
Lissencephaly and cerebellar hypoplasia in a goat
| العنوان: | Lissencephaly and cerebellar hypoplasia in a goat |
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| المؤلفون: | José Rômulo Soares dos Santos, Antônio Flavio Medeiros Dantas, Clarice Ricardo Macedo Pessoa, Tatiane Rodrigues Silva, Sara Vilar Dantas Simões, Franklin Riet Correa, Daniel Pedrosa |
| المصدر: | Ciência Rural, Vol 43, Iss 10, Pp 1858-1861 (2013) |
| بيانات النشر: | Universidade Federal de Santa Maria, 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Agriculture LCC:Agriculture (General) |
| مصطلحات موضوعية: | agiria, hipolplasia cerebelar, caprinos, malformações, Agriculture, Agriculture (General), S1-972 |
| الوصف: | A case of lissencephaly and cerebellar hypoplasia was observed in a 30-day-old goat. The goat presented with sternal recumbence, absence of a menace response, intention tremors, ataxia, and nystagmus. The goat was euthanized and necropsied after having been hospitalised for eleven days. At necropsy, the surface of the brain was found to be smooth, the cerebral sulci and gyri were absent, and the cerebellum was reduced in size. Histologically, the grey matter and white matter were thicker and thinner than normal in cortices, respectively. The neurons were randomly arranged in the grey matter. In the cerebellum, the layers were disorganised, and cells were heterotopics. The histologic and gross lesions observed in this animal are characteristic of lissencephaly associated with cerebellar hypoplasia. The presence of a single goat affected suggests that the malformation was not of infectious origin and because lissencephaly is a malformation not previously described in goats, it is unlikely this case was inherited. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 1678-4596 0103-8478 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013001000020&lng=en&tlng=en; https://doaj.org/toc/1678-4596 |
| DOI: | 10.1590/S0103-84782013001000020 |
| URL الوصول: | https://doaj.org/article/98d503de11c04040b0552d42ad042452 |
| رقم الانضمام: | edsdoj.98d503de11c04040b0552d42ad042452 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 16784596 01038478 |
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| DOI: | 10.1590/S0103-84782013001000020 |