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Granulomatous lithiasic cholecystitis in sarcoidosis

التفاصيل البيبلوغرافية
العنوان: Granulomatous lithiasic cholecystitis in sarcoidosis
المؤلفون: Adriana Handra-Luca
المصدر: Clinics and Practice, Vol 6, Iss 1 (2016)
بيانات النشر: MDPI AG, 2016.
سنة النشر: 2016
المجموعة: LCC:Medicine (General)
مصطلحات موضوعية: Gallbladder, cholecystitis, lithiasis, granuloma, nerve, perineural, Medicine (General), R5-920
الوصف: Gallbladder granulomas are exceedingly rare, reported in association with tuberculosis or sarcoidosis. Here we report a case of gallbladder granulomatous cholecystitis occurring in the context of sarcoidosis. A 70-years old man presented with abdominal pain, nausea and vomiting. The medical history revealed sarcoidosis diagnosed more than 20-years previously. 2-years previously the patient showed renal lithiasis, hypercalcemia and, increased angiotensin converting enzyme. The imaging features suggested thoraco-abdominal sarcoidosis. Prednisone was given at 1.2 mg/kg/day initially, than decreased, being at 2.5 mg/day at present. The ultrasound examination showed gallbladder lithiasis. A cholecystectomy was performed. Microscopy showed subacute and chronic cholecystitis with several epithelioid and giant cell granulomas some of them perineural. In conclusion, we report a case of granulomatous cholecystitis occurring in the course of treated sarcoidosis. The perineural location of granulomas may give further insights into the pathogenesis of gallbladder dysmotility.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2039-7275
2039-7283
Relation: https://www.clinicsandpractice.org/index.php/cp/article/view/811; https://doaj.org/toc/2039-7275; https://doaj.org/toc/2039-7283
DOI: 10.4081/cp.2016.811
URL الوصول: https://doaj.org/article/98cd8e8a56e04644ab3b31493eda233c
رقم الانضمام: edsdoj.98cd8e8a56e04644ab3b31493eda233c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20397275
20397283
DOI:10.4081/cp.2016.811