Academic Journal
Onychomycosis caused by dematiaceous fungi: A four-year study among agricultural workers of Assam, India
| العنوان: | Onychomycosis caused by dematiaceous fungi: A four-year study among agricultural workers of Assam, India |
|---|---|
| المؤلفون: | Parismita Borgohain, Purnima Barua, Lakhi Saikia, Jagadish Mahanta, Dipika Shaw, Shivaprakash Rudramurthy |
| المصدر: | Current Medical Mycology, Vol 9, Iss 3, Pp 8-15 (2023) |
| بيانات النشر: | Mazandaran University of Medical Sciences, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Internal medicine LCC:Biology (General) |
| مصطلحات موضوعية: | nail infection, non-dermatophytes, phaeoid fungi, phytopathogens, Internal medicine, RC31-1245, Biology (General), QH301-705.5 |
| الوصف: | Background and Purpose: Onychomycosis due to dematiaceous fungi is rarely reported and the identification is also quite tricky due to poor sporulation.The recent emergence of dematiaceous fungi as a cause major of onychomycosis is a matter of concern in the field of mycology. Therefore, this study aimed to understand the dematiaceous fungi as a possible cause of onychomycosis, especially among agricultural workers. In addition, the evaluation of the antifungal susceptibility patterns gave an idea of the accurate drug that will help in the treatment challenge and prevent antifungal resistance. Materials and Methods: The standard procedure was followed for direct microscopic examination and isolating fungi. Furthermore, antifungal susceptibility testing (AFST) was conducted in accordance with the Clinical and Laboratory Standards Institute (CLSI) M-38-A2 protocol.Results: Both KOH and fungal positivity were recovered in 275 workers out of 356 suspected cases, of which 52% were NDMs, 4.3% were yeast, 28.7% were dermatophytes and 14.9% were sterile hyphae. Among NDMs (52%, n=143), 45.5% (n=65) were hyaline hyphomycetes and 54.5% (n=78) were dematiaceous hyphomycetes. Among dematiaceous fungi, Pestalotiopsis spp., Arthrinium spp., etc. were commonly isolated. Additionally, azoles, amphotericin-B and anidulafungin showed excellent antifungal activity against tested isolates. Conclusion: Dematiaceous fungi are now becoming a potential cause of onychomycosis. A more detailed study is needed on the identification of these emerging isolates and the mode of action of antifungal drugs for a better treatment strategy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2423-3439 2423-3420 |
| Relation: | https://cmm.mazums.ac.ir/article_150692_30cf83034bbc03f87138b54d3a8dce3b.pdf; https://doaj.org/toc/2423-3439; https://doaj.org/toc/2423-3420 |
| DOI: | 10.22034/cmm.2023.345077.1428 |
| URL الوصول: | https://doaj.org/article/cc9895b7f96b47a78c3387d9efb3b8ca |
| رقم الانضمام: | edsdoj.9895b7f96b47a78c3387d9efb3b8ca |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24233439 24233420 |
|---|---|
| DOI: | 10.22034/cmm.2023.345077.1428 |