Academic Journal
Neonatal cholestasis - Single centre experience in Central India
| العنوان: | Neonatal cholestasis - Single centre experience in Central India |
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| المؤلفون: | Mayank Jain, Sagar Adkar, Chandrashekhar Waghmare, Jenisha Jain, Shikhar Jain, Kamna Jain, Gouri Rao Passi, Rashmi Shad Vinay, M K Soni |
| المصدر: | Indian Journal of Community Medicine, Vol 41, Iss 4, Pp 299-301 (2016) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Cholestasis, jaundice, neonatal, syndrome, Public aspects of medicine, RA1-1270 |
| الوصف: | Background: Neonatal cholestasis syndrome (NCS) is a major cause of morbidity and mortality in infants. The disorder has rarely been studied in centers from Central India. Objectives: To study the prevalence, clinical presentation and etiology of NCS at a tertiary referral center in Central India. Materials and Methods: The study was carried out at a tertiary referral center in Central India. The study is a descriptive study. The records of all patients with suspected NCS treated in the Department of Pediatrics from 2007−2012 were analyzed. Results: One hundred and sixty-eight children had a provisional diagnosis of NCS. The complete records of 100 children were available for the study. The median age of presentation was 78 days (range 15−270 days). The male: female ratio was 1.17:1. The clinical features noted were- jaundice (100/100,100%), failure to thrive (73,73%), organomegaly (68, 68%), acholic stools (38,38%), abdominal distention (52,52%) and poor feeding (29, 29%). The etiology as confirmed by investigations is as follows- neonatal hepatitis (20,20%), idiopathic neonatal hepatitis (18,18%), biliary atresia (41,41%), sepsis (14,14%) and others (7,7%). Conclusions: The proportion of NCS in our group of patients was 1.2 per 1000 patients. Jaundice, organomegaly and failure to thrive are the common presentations. Biliary atresia, neonatal hepatitis and idiopathic neonatal hepatitis were the common etiological factors at our center. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0970-0218 1998-3581 |
| Relation: | http://www.ijcm.org.in/article.asp?issn=0970-0218;year=2016;volume=41;issue=4;spage=299;epage=301;aulast=Jain; https://doaj.org/toc/0970-0218; https://doaj.org/toc/1998-3581 |
| DOI: | 10.4103/0970-0218.193331 |
| URL الوصول: | https://doaj.org/article/988aac8c55004e3f9d5f195bbe7e62b5 |
| رقم الانضمام: | edsdoj.988aac8c55004e3f9d5f195bbe7e62b5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09700218 19983581 |
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| DOI: | 10.4103/0970-0218.193331 |