Academic Journal

Seroprevalence of hepatitis B virus: Findings from a population-based household survey in KwaZulu-Natal, South Africa

التفاصيل البيبلوغرافية
العنوان: Seroprevalence of hepatitis B virus: Findings from a population-based household survey in KwaZulu-Natal, South Africa
المؤلفون: Natasha Samsunder, Sinaye Ngcapu, Lara Lewis, Cheryl Baxter, Cherie Cawood, David Khanyile, Ayesha B.M. Kharsany
المصدر: International Journal of Infectious Diseases, Vol 85, Iss , Pp 150-157 (2019)
بيانات النشر: Elsevier, 2019.
سنة النشر: 2019
المجموعة: LCC:Infectious and parasitic diseases
مصطلحات موضوعية: Infectious and parasitic diseases, RC109-216
الوصف: Background: Hepatitis B virus (HBV) infection is a major cause of morbidity and mortality; however, little is known about the prevalence and distribution of HBV in some populations and regions. Methods: A total of 9791 participants, 15–49 years old, were enrolled in a household survey in KwaZulu-Natal, South Africa. Peripheral blood samples were tested for markers of HBV (hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg), antibody to HBeAg (anti-HBe)) and analysed, accounting for multilevel sampling and weighted to represent the population. Results: Overall HBsAg prevalence was 4.0% (95% confidence interval (CI) 3.4–4.5%): 4.8% (95% CI 3.8–5.8%) in men and 3.2% (95% CI 2.5–3.9%) in women (p = 0.01). Among HBsAg-positive participants, 35.2% (95% CI 29.2–41.2%) were HBeAg-positive and 66.3% (95% CI 60.1–72.4%) were anti-HBe-positive. HBsAg prevalence was 6.4% (95% CI 5.3–7.5%) among HIV-positive participants compared to 2.6% (95% CI 1.9–3.2%) among HIV-negative participants (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1201-9712
Relation: http://www.sciencedirect.com/science/article/pii/S1201971219302504; https://doaj.org/toc/1201-9712
DOI: 10.1016/j.ijid.2019.06.005
URL الوصول: https://doaj.org/article/d97a1883d9c749e6acf5593ba3d96371
رقم الانضمام: edsdoj.97a1883d9c749e6acf5593ba3d96371
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:12019712
DOI:10.1016/j.ijid.2019.06.005