التفاصيل البيبلوغرافية
| العنوان: |
N,N-Bis(hexyl α-d-acetylmannosyl) Acrylamide |
| المؤلفون: |
Atsushi Miyagawa, Shinya Ohno, Hatsuo Yamamura |
| المصدر: |
Molbank, Vol 2021, Iss 3, p M1255 (2021) |
| بيانات النشر: |
MDPI AG, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Inorganic chemistry |
| مصطلحات موضوعية: |
glycosyl monomer, acryloylation, acrylamide, glycopolymer, bivalent ligand, Inorganic chemistry, QD146-197 |
| الوصف: |
Glycosyl monomers for the assembly of multivalent ligands are typically synthesized using carbohydrates with biological functions and polymerizable functional groups such as acrylamide or styrene introduced into the carbohydrate aglycon, and monomers polymerized using a radical initiator. Herein, we report the acryloylation of 6-aminohexyl α-d-mannoside and its conversion into the glycosyl monomer bearing an acrylamide group. The general acryloylation procedure afforded the desired N-hexyl α-d-acetylmannosyl acrylamide monomer as well as an unexpected compound with a close Rf value. The compounds were separated and analyzed by nuclear magnetic resonance spectroscopy and mass spectrometry, which revealed the unknown compound to be the bivalent N,N-bis(hexyl α-d-acetylmannosyl) acrylamide monomer, which contains two hexyl mannose units and one acrylamide group. To the best of our knowledge, this side reaction has not previously been disclosed, and may be useful for the construction of multivalent sugar ligands. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1422-8599 |
| Relation: |
https://www.mdpi.com/1422-8599/2021/3/M1255; https://doaj.org/toc/1422-8599 |
| DOI: |
10.3390/M1255 |
| URL الوصول: |
https://doaj.org/article/e93bcbcfb63c40cd9217dc152ebc12f8 |
| رقم الانضمام: |
edsdoj.93bcbcfb63c40cd9217dc152ebc12f8 |
| قاعدة البيانات: |
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