Academic Journal
State-dependent coupling of hippocampal oscillations
| العنوان: | State-dependent coupling of hippocampal oscillations |
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| المؤلفون: | Brijesh Modi, Matteo Guardamagna, Federico Stella, Marilena Griguoli, Enrico Cherubini, Francesco P Battaglia |
| المصدر: | eLife, Vol 12 (2023) |
| بيانات النشر: | eLife Sciences Publications Ltd, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Science LCC:Biology (General) |
| مصطلحات موضوعية: | oscillations, coupling, state space, sleep, syncrhonization, state dependent, Medicine, Science, Biology (General), QH301-705.5 |
| الوصف: | Oscillations occurring simultaneously in a given area represent a physiological unit of brain states. They allow for temporal segmentation of spikes and support distinct behaviors. To establish how multiple oscillatory components co-vary simultaneously and influence neuronal firing during sleep and wakefulness in mice, we describe a multivariate analytical framework for constructing the state space of hippocampal oscillations. Examining the co-occurrence patterns of oscillations on the state space, across species, uncovered the presence of network constraints and distinct set of cross-frequency interactions during wakefulness compared to sleep. We demonstrated how the state space can be used as a canvas to map the neural firing and found that distinct neurons during navigation were tuned to different sets of simultaneously occurring oscillations during sleep. This multivariate analytical framework provides a window to move beyond classical bivariate pipelines for investigating oscillations and neuronal firing, thereby allowing to factor-in the complexity of oscillation–population interactions. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2050-084X |
| Relation: | https://elifesciences.org/articles/80263; https://doaj.org/toc/2050-084X |
| DOI: | 10.7554/eLife.80263 |
| URL الوصول: | https://doaj.org/article/92f0199de2f142268f97640284c52323 |
| رقم الانضمام: | edsdoj.92f0199de2f142268f97640284c52323 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2050084X |
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| DOI: | 10.7554/eLife.80263 |