التفاصيل البيبلوغرافية
| العنوان: |
Extracellular vesicles and endothelial dysfunction in infectious diseases |
| المؤلفون: |
Linfang Zhang, Jingshu Chi, Hao Wu, Xiujuan Xia, Canxia Xu, Hong Hao, Zhenguo Liu |
| المصدر: |
Journal of Extracellular Biology, Vol 3, Iss 4, Pp n/a-n/a (2024) |
| بيانات النشر: |
Wiley, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Cytology |
| مصطلحات موضوعية: |
cardiovascular diseases, endothelial dysfunction, exosomes, extracellular vesicles, Helicobacter pylori, infectious diseases, Cytology, QH573-671 |
| الوصف: |
Abstract Cardiovascular diseases (CVDs) remain the leading cause of mortality and morbidity globally. Studies have shown that infections especially bacteraemia and sepsis are associated with increased risks for endothelial dysfunction and related CVDs including atherosclerosis. Extracellular vesicles (EVs) are small, sealed membrane‐derived structures that are released into body fluids and blood from cells and/or microbes and are critically involved in a variety of important cell functions and disease development, including intercellular communications, immune responses and inflammation. It is known that EVs‐mediated mechanism(s) is important in the development of endothelial dysfunction in infections with a diverse spectrum of microorganisms including Escherichia coli, Candida albicans, SARS‐CoV‐2 (the virus for COVID‐19) and Helicobacter pylori. H. pylori infection is one of the most common infections globally. During H. pylori infection, EVs can carry H. pylori components, such as lipopolysaccharide, cytotoxin‐associated gene A, or vacuolating cytotoxin A, and transfer these substances into endothelial cells, triggering inflammatory responses and endothelial dysfunction. This review is to illustrate the important role of EVs in the pathogenesis of infectious diseases, and the development of endothelial dysfunction in infectious diseases especially H. pylori infection, and to discuss the potential mechanisms and clinical implications. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2768-2811 |
| Relation: |
https://doaj.org/toc/2768-2811 |
| DOI: |
10.1002/jex2.148 |
| URL الوصول: |
https://doaj.org/article/eed92eb2abf248af872008b673681e60 |
| رقم الانضمام: |
edsdoj.92eb2abf248af872008b673681e60 |
| قاعدة البيانات: |
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