التفاصيل البيبلوغرافية
| العنوان: |
Sorbicillinoid Derivatives From Sponge-Derived Fungus Trichoderma reesei (HN-2016-018) |
| المؤلفون: |
Saif Ur Rehman, Lu-Jia Yang, Ya-Hui Zhang, Jing-Shuai Wu, Ting Shi, Waqas Haider, Chang-Lun Shao, Chang-Yun Wang |
| المصدر: |
Frontiers in Microbiology, Vol 11 (2020) |
| بيانات النشر: |
Frontiers Media S.A., 2020. |
| سنة النشر: |
2020 |
| المجموعة: |
LCC:Microbiology |
| مصطلحات موضوعية: |
sponge-derived fungus, Trichoderma reesei, sorbicillinoid, naphthalene-trione, cytotoxic activity, Microbiology, QR1-502 |
| الوصف: |
Six new sorbicillinoids, trichoreeseione A (1) and B (2), trichodermolide B (3), 13-hydroxy-trichodermolide (4), 24-hydroxy-trichodimerol (5), 15-hydroxy-bisvertinol (7), together with three known analogs, trichodimerol (6), 24-hydroxy-bisvertinol (8), and bisvertinol (9), were isolated from the sponge-derived fungus Trichoderma reesei (HN-2016-018). Their structures including absolute configurations were elucidated by analysis of NMR, MS data, and calculated ECD spectra. Compounds 1 and 2 with a characteristic naphthalene-trione ring were firstly reported in sorbicillinoid family. Compounds 3 and 4 were two rare sorbicillinoids containing a unique bicycle [3.2.1] lactone skeleton, while 3 with a propan-2-one moiety was also recorded first time in this family. Compound 5 displayed cytotoxic activity against A549, MCF-7, and HCT116 cell lines with the IC50 values of 5.1, 9.5, and 13.7 μM, respectively. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1664-302X |
| Relation: |
https://www.frontiersin.org/article/10.3389/fmicb.2020.01334/full; https://doaj.org/toc/1664-302X |
| DOI: |
10.3389/fmicb.2020.01334 |
| URL الوصول: |
https://doaj.org/article/92a7099e76f94bd78f091c0691110b69 |
| رقم الانضمام: |
edsdoj.92a7099e76f94bd78f091c0691110b69 |
| قاعدة البيانات: |
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