Academic Journal
Evaluation of sexual functional status and consistency of scales in patients with hypogonadotropic hypogonadism before and after testosterone replacement therapy: a single-center experience
| العنوان: | Evaluation of sexual functional status and consistency of scales in patients with hypogonadotropic hypogonadism before and after testosterone replacement therapy: a single-center experience |
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| المؤلفون: | Umit Aydogan, Yusuf Cetin Doganer, Cem Haymana, Umit Kaplan, Aydogan Aydogdu, Ibrahim Demirci, Coskun Meric, Yusuf Alper Sonmez |
| المصدر: | Archives of Endocrinology and Metabolism, Vol 67, Iss 2, Pp 179-188 (2023) |
| بيانات النشر: | Brazilian Society of Endocrinology and Metabolism, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: | Hypogonadotropic hypogonadism, sexual functions, testosterone replacement therapy, Medicine, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: | ABSTRACT Objective: This study aimed to investigate the frequency of sexual dysfunction and the effect of short-term testosterone replacement therapy on sexual functions in congenital hypogonadism patients. Furthermore, we sought to reveal the consistency of the self-report scales used for the diagnosis of sexual dysfunction and the relationship between biochemical parameters. Materials and methods: The study was conducted on 47 young male patients aged above 18 years who were diagnosed with hypogonadotropic hypogonadism. Short (IIEF-5) and long (IIEF-15) forms of the International Index of Erectile Function and Arizona Sexual Experiences Scale (ASEX) were applied before treatment under the supervision of a physician. The patients’ blood pressure, height, and weight were measured, and their luteinizing hormone (LH), FSH, and total testosterone levels were recorded. Patients who started their treatments were called for a follow-up checkup after 6 months. Their blood pressure, height, and weight were measured by reapplying the ASEX, IIEF-5, and IIEF-15. In addition, their LH, FSH, and total testosterone levels in the biochemical tests were rerecorded. Results: In this study, the sexual dysfunction status of patients diagnosed with hypogonadotropic hypogonadism before and after treatment was evaluated using the ASEX, IIEF-15, and IIEF-5 scales. A decrease in sexual dysfunction was observed in all three scales after treatment compared with that before treatment. The IIEF-5 and IIEF-15 scales were found to be uncorrelated in terms of the pretreatment values but were correlated in terms of the post-treatment values. Although a correlation was observed between ASEX and IIEF-5 before treatment, no correlation was detected between ASEX and IIEF-15. After the treatment, ASEX was found to be correlated with both IIEF-5 and IIEF-15. The results of the scales indicated the correlation in all categories, except the pretreatment results of the IIEF-15 scale. Conclusion: The results of the current study demonstrated a significant improvement in the sexual function of hypogonadism patients undergoing short-term testosterone therapy. The ASEX, IIEF-5, and IIEF-15 scales used in the diagnosis and follow-up of sexual dysfunction were useful for evaluating sexual functions in hypogonadotropic hypogonadism patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2359-4292 2359-3997 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972023000200179&lng=en&tlng=en; http://www.scielo.br/pdf/aem/v67n2/2359-4292-aem-2359-3997000000539.pdf; https://doaj.org/toc/2359-4292 |
| DOI: | 10.20945/2359-3997000000539 |
| URL الوصول: | https://doaj.org/article/c928131d5d3b4bcd8c4db939fde8b17c |
| رقم الانضمام: | edsdoj.928131d5d3b4bcd8c4db939fde8b17c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23594292 23593997 |
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| DOI: | 10.20945/2359-3997000000539 |