Academic Journal

Statistical modelling to predict silicosis risk in deceased Southern African gold miners without medical evaluation

التفاصيل البيبلوغرافية
العنوان: Statistical modelling to predict silicosis risk in deceased Southern African gold miners without medical evaluation
المؤلفون: Jonathan E. Myers, Mary Lou Thompson
المصدر: South African Journal of Science, Vol 118, Iss 7/8 (2022)
بيانات النشر: Academy of Science of South Africa, 2022.
سنة النشر: 2022
المجموعة: LCC:Science
LCC:Science (General)
LCC:Social Sciences
LCC:Social sciences (General)
مصطلحات موضوعية: gold miner, silicosis, risk prediction, statistical model, classification accuracy, Science, Science (General), Q1-390, Social Sciences, Social sciences (General), H1-99
الوصف: The Qhubeka Trust was established in 2016 in a legal settlement on behalf of former gold miners seeking compensation for silicosis contracted on the South African mines. Settlements resulting from lawsuits on behalf of gold miners aim to provide fair compensation. However, occupational exposure and medical records kept by South African mining companies for their employees have been very limited. Some claimants to the Qhubeka Trust died before medical evaluation was possible, thus potentially disadvantaging their dependants from receiving any compensation. With medical evaluation no longer possible, a statistical approach to this problem was developed. The records for claimants with medical evaluation were used to develop a logistic regression prediction model for the likelihood of silicosis, based on the potential predictors: cumulative exposure to respirable dust, age, years since first exposure, years of life lost prematurely, vital status at 31 December 2019, and a history of tuberculosis diagnosis. The prediction model allowed estimation of the likelihood of silicosis for each miner who had died without medical evaluation and is a novel approach in this setting. In addition, we were able to quantitatively evaluate the trade-offs of different silicosis risk classification thresholds in terms of true and false positives and negatives. Significance: • A statistical approach can be used for risk estimation in settings where the outcome of interest is unknown for some members of a class. • The likelihood of silicosis in deceased miners without medical evaluation in the Qhubeka Trust can be accurately estimated, using information from finalised claims. • Strategies for classifying the silicosis status of deceased miners without medical evaluation in the Qhubeka Trust can be assessed in a rigorous, quantitative framework.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1996-7489
Relation: https://sajs.co.za/article/view/12502; https://doaj.org/toc/1996-7489
DOI: 10.17159/sajs.2022/12502
URL الوصول: https://doaj.org/article/910407d92a5a44ab9a287497f8482b28
رقم الانضمام: edsdoj.910407d92a5a44ab9a287497f8482b28
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19967489
DOI:10.17159/sajs.2022/12502