التفاصيل البيبلوغرافية
| العنوان: |
Real-Time and Ultrasensitive Prostate-Specific Antigen Sensing Using Love-Mode Surface Acoustic Wave Immunosensor Based on MoS2@Cu2O-Au Nanocomposites |
| المؤلفون: |
Yan Yu, Haiyu Xie, Tao Zhou, Haonan Zhang, Chenze Lu, Ran Tao, Zhaozhao Tang, Jingting Luo |
| المصدر: |
Sensors, Vol 24, Iss 23, p 7636 (2024) |
| بيانات النشر: |
MDPI AG, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Chemical technology |
| مصطلحات موضوعية: |
Love-mode surface acoustic wave (L-SAW), immunosensor, nanocomposite, prostate-specific antigen (PSA), real time, ultrasensitive, Chemical technology, TP1-1185 |
| الوصف: |
Prostate-specific antigen (PSA) is a well-established tumour marker for prostatic carcinoma. In this study, we present a novel, real-time, and ultrasensitive Love-mode surface acoustic wave (L-SAW) immunosensor for PSA detection enhanced by MoS2@Cu2O-Au nanocomposite conjugation. The MoS2@Cu2O-Au nanocomposites were analyzed by SEM, XRD, and EDS. The experiments show a significant improvement in sensitivity and detection limit compared with the previous detection methods utilizing nanogold alone to detect PSA biomolecules. The experimental results show a good linear relationship when the range of PSA concentrations between 200 pg/mL and 5 ng/mL was tested. The experimental results also show good specificity against alpha 1 fetoprotein and L-tryptophan disruptors. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1424-8220 |
| Relation: |
https://www.mdpi.com/1424-8220/24/23/7636; https://doaj.org/toc/1424-8220 |
| DOI: |
10.3390/s24237636 |
| URL الوصول: |
https://doaj.org/article/e90f6eef8c644a63955f4b8f5fe41a7f |
| رقم الانضمام: |
edsdoj.90f6eef8c644a63955f4b8f5fe41a7f |
| قاعدة البيانات: |
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