Academic Journal
Cobalt (II) Complexes with Schiff Base Ligands Derived from Terephthalaldehyde and ortho-Substituted Anilines: Synthesis, Characterization and Antibacterial Activity
العنوان: | Cobalt (II) Complexes with Schiff Base Ligands Derived from Terephthalaldehyde and ortho-Substituted Anilines: Synthesis, Characterization and Antibacterial Activity |
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المؤلفون: | Sahar Shaygan, Hoda Pasdar, Naser Foroughifar, Mehran Davallo, Fereshteh Motiee |
المصدر: | Applied Sciences, Vol 8, Iss 3, p 385 (2018) |
بيانات النشر: | MDPI AG, 2018. |
سنة النشر: | 2018 |
المجموعة: | LCC:Technology LCC:Engineering (General). Civil engineering (General) LCC:Biology (General) LCC:Physics LCC:Chemistry |
مصطلحات موضوعية: | terephthalaldehyde, ortho-aniline derivatives, Schiff base ligand, antibacterial activity, disc diffusion method, broth dilution method, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999 |
الوصف: | In this study, N-propyl-benzoguanamine-SO3H magnetic nanoparticles (MNPs) were used as a catalyst for the synthesis of new Schiff base ligands from condensation reaction of terephthalaldehyde and ortho-aniline derivatives. The bioactive ligands and their cobalt (II) complexes were characterized with nuclear magnetic resonance (1H-NMR), Fourier-transform infrared spectroscopy (FT-IR), ultraviolet-visible (UV-Visible), mass spectroscopy studies and molar conductance. The antibacterial activity of ligands and their metal complexes were screened using disc diffusion and broth dilution methods against Escherichia coli, Serratia marcescens, Pseudomonas aeruginosa (gram negative bacteria), Bacillus Subtilis and Staphylococcus aureus (gram positive bacteria). The ligands with hydroxyl group showed better biological activity when compared to other ligands. The results showed that the metal complexes have much higher antibacterial activity compare to the parent ligands. It was found that the CoL3 complex was more effective than other metal complexes used against all types of bacteria tested and it was more effective against Pseudomonas aeruginosa with diameter inhibition zone of 17 mm and minimal inhibitory concentration value of 0.15 mg/mL. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2076-3417 |
Relation: | http://www.mdpi.com/2076-3417/8/3/385; https://doaj.org/toc/2076-3417 |
DOI: | 10.3390/app8030385 |
URL الوصول: | https://doaj.org/article/90cb4254dd984bf29b4300cc0ab5fc04 |
رقم الانضمام: | edsdoj.90cb4254dd984bf29b4300cc0ab5fc04 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20763417 |
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DOI: | 10.3390/app8030385 |