Academic Journal

Lack of genotoxicity of iron oxide maghemite (γ-Fe2O3) and magnetite (Fe3O4) nanoparticles to Oreochromis niloticus after acute exposures

التفاصيل البيبلوغرافية
العنوان: Lack of genotoxicity of iron oxide maghemite (γ-Fe2O3) and magnetite (Fe3O4) nanoparticles to Oreochromis niloticus after acute exposures
المؤلفون: Maria Luiza Fascineli, Paolin Rocio Cáceres-Vélez, Willie Oliveira Pinheiro, Sacha Braun Chaves, Marcelo Henrique Sousa, Wilson Sacchi Peternella, Frederico Hillesheim Horst, Michele de Castro Fernandes, Wania Guimarães, Ricardo Bentes Azevedo, Cesar Koppe Grisolia
المصدر: Genetics and Molecular Biology, Vol 47, Iss 3 (2024)
بيانات النشر: Sociedade Brasileira de Genética, 2024.
سنة النشر: 2024
المجموعة: LCC:Genetics
مصطلحات موضوعية: Magnetite, maghemite, tilapia fish, nanotoxicology, nanoparticles, Genetics, QH426-470
الوصف: Abstract Iron oxide nanoparticles (FeO-NPs) are widely used in scientific and technological fields. Environmental concerns have been raised about residual FeO-NPs levels as their toxicity and bioaccumulative potential are not well understood. Oreochromis niloticus were exposed to nanoparticles of γ-Fe2O3 and Fe3O4. Micro-CT 3D image and grayscale graphic assessments revealed the accumulation of radiopaque material in the digestive tract of fish exposed to FeO-NPs. Histological analysis showed the presence of such NPs in the hepatopancreas, gills, kidneys, and muscles. No genotoxicity occurred, through micronucleus test and comet assay in peripheral erythrocytes. Body clearance was confirmed by iron-content reduction in organisms exposed to FeO-NPs after recovery period. No tissue injuries were observed in the exposed animals which may be attributed to the absence or low toxicity of iron oxide nanoparticles under the study conditions. O. niloticus showed tolerance to sublethal exposures to FeO-NPs.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1678-4685
Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572024000400502&lng=en&tlng=en; http://www.scielo.br/pdf/gmb/v47n3/1415-4757-GMB-47-03-e20230330.pdf; https://doaj.org/toc/1678-4685
DOI: 10.1590/1678-4685-gmb2023-0330
URL الوصول: https://doaj.org/article/d8fa37ec786b4e04b0379fb3aef31495
رقم الانضمام: edsdoj.8fa37ec786b4e04b0379fb3aef31495
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16784685
DOI:10.1590/1678-4685-gmb2023-0330