Academic Journal
Copper(I)-catalyzed tandem reaction: synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and alkynes
| العنوان: | Copper(I)-catalyzed tandem reaction: synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and alkynes |
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| المؤلفون: | Muhammad Israr, Changqing Ye, Munira Taj Muhammad, Yajun Li, Hongli Bao |
| المصدر: | Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2916-2922 (2018) |
| بيانات النشر: | Beilstein-Institut, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Science LCC:Organic chemistry |
| مصطلحات موضوعية: | alkyl diacyl peroxides, azidotrimethylsilane, click reaction, copper catalysis, radical, 1,2,3-triazoles, Science, Organic chemistry, QD241-441 |
| الوصف: | A copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction for the synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and terminal alkynes is reported. The alkyl carboxylic acids is for the first time being used as the alkyl azide precursors in the form of alkyl diacyl peroxides. This method avoids the necessity to handle organic azides, as they are generated in situ, making this protocol operationally simple. The Cu(I) catalyst not only participates in the alkyl diacyl peroxides decomposition to afford alkyl azides but also catalyzes the subsequent CuAAC reaction to produce the 1,2,3-triazoles. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1860-5397 |
| Relation: | https://doaj.org/toc/1860-5397 |
| DOI: | 10.3762/bjoc.14.270 |
| URL الوصول: | https://doaj.org/article/8fa159fa4b404e639c6e61edcd684778 |
| رقم الانضمام: | edsdoj.8fa159fa4b404e639c6e61edcd684778 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18605397 |
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| DOI: | 10.3762/bjoc.14.270 |