التفاصيل البيبلوغرافية
| العنوان: |
Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling |
| المؤلفون: |
Shouya Feng, Daniel Enosi Tuipulotu, Abhimanu Pandey, Weidong Jing, Cheng Shen, Chinh Ngo, Melkamu B. Tessema, Fei-Ju Li, Daniel Fox, Anukriti Mathur, Anyang Zhao, Runli Wang, Klaus Pfeffer, Daniel Degrandi, Masahiro Yamamoto, Patrick C. Reading, Gaetan Burgio, Si Ming Man |
| المصدر: |
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022) |
| بيانات النشر: |
Nature Portfolio, 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Science |
| مصطلحات موضوعية: |
Science |
| الوصف: |
Guanylate-binding proteins (GBP) have a function in inflammasome formation and pathogen defence. Here the authors show that these GBP proteins are able to kill certain bacteria and promote selective inflammasome activation and that this is mediated by specific GBP protein regions. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-32127-0 |
| URL الوصول: |
https://doaj.org/article/ea8e4a282bec420d92c49592fcff8122 |
| رقم الانضمام: |
edsdoj.8e4a282bec420d92c49592fcff8122 |
| قاعدة البيانات: |
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