Academic Journal
Does the serum uric acid level have any relation to arterial stiffness or blood pressure in adults with congenital renal agenesis and/or hypoplasia?
| العنوان: | Does the serum uric acid level have any relation to arterial stiffness or blood pressure in adults with congenital renal agenesis and/or hypoplasia? |
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| المؤلفون: | Raziye Yazici, İbrahim Guney, Lutfullah Altintepe, Mehmet Yazici |
| المصدر: | Clinical and Experimental Hypertension, Vol 39, Iss 2, Pp 145-149 (2017) |
| بيانات النشر: | Taylor & Francis Group, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | arterial stiffness, hypoplastic kidney, pulse wave velocity, renal agenesia, uric acid, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Background: The relationship between serum uric acid and arterial stiffness or blood pressure is not clear. The serum uric acid level and its association with cardiovascular risk is not well known in patients with reduced renal mass. We aimed to investigate the relation between serum uric acid levels and arterial stiffness and also blood pressure in patients with congenital renal agenesis and/or hypoplasia. Material and Methods: In this single center, cross-sectional study, a total of 55 patients (39 (% 70.9) with unilateral small kidney and 16 (%29.1) with renal agenesis) were included. The median age was 35 (21–50) years. The study population was divided into tertiles of serum uric acid (according to 2.40–3.96, 3.97–5.10, and 5.11–9.80 mg/dl cut-off values of serum uric acid levels). Official and 24-h ambulatory non-invasive blood pressures of all patients were measured. The arterial stiffness was assessed by pulse wave velocity (PWV). Results: PWV values were increased from first to third tertile (5.5 ± 0.6, 5.7 ± 0.8, 6.1 ± 0.7, respectively), but this gradual increase between tertiles did not reach significance. Linear regression analyses showed a positive correlation between serum uric acid levels and PWV (β = 0.40, p = 0.010), but no correlation was found between uric acid and daytime systolic blood pressure (β = 0.24, p = 0.345). Conclusion: In congenital renal agenesis/hypoplasia, the serum uric acid level was positively correlated with arterial stiffness, but there was no correlation with blood pressure. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1064-1963 1525-6006 10641963 |
| Relation: | https://doaj.org/toc/1064-1963; https://doaj.org/toc/1525-6006 |
| DOI: | 10.1080/10641963.2016.1210630 |
| URL الوصول: | https://doaj.org/article/8df66d2d86744dd6b782f8a966b724de |
| رقم الانضمام: | edsdoj.8df66d2d86744dd6b782f8a966b724de |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 10641963 15256006 |
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| DOI: | 10.1080/10641963.2016.1210630 |