Academic Journal
Retrospective review of pediatric status epilepticus in 116 Saudi patients: predictors of outcome
| العنوان: | Retrospective review of pediatric status epilepticus in 116 Saudi patients: predictors of outcome |
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| المؤلفون: | Raid Harb Hommady, Muhammad Talal Alrifai, Osama Khaled Mubayrik, Ruba Salem Alayed, Muhannad Abdulrahman Alsemari, Ahmed Arumayyan, Waleed Altuwaijri, Duaa Baarmah |
| المصدر: | Annals of Saudi Medicine, Vol 37, Iss 6, Pp 455-460 (2017) |
| بيانات النشر: | King Faisal Specialist Hospital and Research Centre, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | Medicine |
| الوصف: | BACKGROUND: Status epilepticus (SE) is a common, life-threatening condition. Multiple factors are used to predict its outcome and evaluate its risks, and there have been only a few studies in Saudi Arabia. OBJECTIVES: Investigate predictors of SE outcome. DESIGN: Retrospective chart review study. SETTING: Tertiary center, Riyadh. PATIENTS AND METHODS: We reviewed all pediatric cases (age 14 years or younger) of SE admitted between January 2005 and December 2015, collecting data on age, sex, date of birth, developmental status, pre-existing neurological diseases, SE etiology, Glasgow Outcome Scale (GOS) scores, and electroencephalogram (EEG) findings. The outcome was categorized as poor based on any decrease in baseline GOS score or moderate-to-severe developmental delay in young children; otherwise outcome was considered good. MAIN OUTCOME MEASURE: Outcome of SE. RESULTS: One hundred and sixteen patients (54% boys) with ages from 1 month to 10 years were included in the analysis. Fifty-five (47.4%) had a poor outcome. The overall mortality rate related to SE was 2.6%. Four patients had an SE duration of more than 24 hours. Univariate and multivariate analysis revealed that poor outcome was related to symptomatic SE etiology and a history of epilepsy. Age, sex, SE duration, and EEG findings were not predictors of poor outcome. CONCLUSION: Pediatric status epilepticus is highly associated with neurological morbidity. The main predictor of outcome is underlying symptomatic etiology of SE and to a lesser degree the presence of a history of epilepsy. Duration does not seem to play a major role. LIMITATIONS: The main limitation is the retrospective chart review nature of the study with possible bias. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0256-4947 0975-4466 |
| Relation: | https://doaj.org/toc/0256-4947; https://doaj.org/toc/0975-4466 |
| DOI: | 10.5144/0256-4947.2017.455 |
| URL الوصول: | https://doaj.org/article/e8b934a4bb4d4189b1ad7e5cdb9e7bd7 |
| رقم الانضمام: | edsdoj.8b934a4bb4d4189b1ad7e5cdb9e7bd7 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 02564947 09754466 |
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| DOI: | 10.5144/0256-4947.2017.455 |