Academic Journal
GBCdb: RNA expression landscapes and ncRNA–mRNA interactions in gallbladder carcinoma
العنوان: | GBCdb: RNA expression landscapes and ncRNA–mRNA interactions in gallbladder carcinoma |
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المؤلفون: | Li Guo, Yangyang Xiang, Yuyang Dou, Zibo Yin, Xinru Xu, Lihua Tang, Jiafeng Yu, Jun Wang, Tingming Liang |
المصدر: | BMC Bioinformatics, Vol 24, Iss 1, Pp 1-10 (2023) |
بيانات النشر: | BMC, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Computer applications to medicine. Medical informatics LCC:Biology (General) |
مصطلحات موضوعية: | Gallbladder carcinoma (GBC), Multi-omics, Expression landscape, RNA interaction, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5 |
الوصف: | Abstract Gallbladder carcinoma (GBC), an aggressive malignant tumor of the biliary system, is characterized by high cellular heterogeneity and poor prognosis. Fewer data have been reported in GBC than other common cancer types. Multi-omics data will contribute to the understanding of the molecular mechanisms of cancer, cancer diagnosis and prognosis. Herein, to provide better understanding of the molecular events in GBC pathogenesis, we developed GBCdb ( http://tmliang.cn/gbc/ ), a user-friendly interface for the query and browsing of GBC-associated genes and RNA interaction networks using published multi-omics data, which also included experimentally supported data from different molecular levels. GBCdb will help to elucidate the potential biological roles of different RNAs and allow for the exploration of RNA interactions in GBC. These resources will provide an opportunity for unraveling the potential molecular features of Gallbladder carcinoma. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1471-2105 |
Relation: | https://doaj.org/toc/1471-2105 |
DOI: | 10.1186/s12859-023-05133-2 |
URL الوصول: | https://doaj.org/article/8b0927a9f02c45d7ae35b80eff26fad0 |
رقم الانضمام: | edsdoj.8b0927a9f02c45d7ae35b80eff26fad0 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14712105 |
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DOI: | 10.1186/s12859-023-05133-2 |