Academic Journal

Defatted Rice Bran Supplementation in Diets of Finishing Pigs: Effects on Physiological, Intestinal Barrier, and Oxidative Stress Parameters

التفاصيل البيبلوغرافية
العنوان: Defatted Rice Bran Supplementation in Diets of Finishing Pigs: Effects on Physiological, Intestinal Barrier, and Oxidative Stress Parameters
المؤلفون: Lijuan Fan, Ruihua Huang, Chengwu Wu, Yang Cao, Taoran Du, Guang Pu, Huan Wang, Wuduo Zhou, Pinghua Li, Sung Woo Kim
المصدر: Animals, Vol 10, Iss 3, p 449 (2020)
بيانات النشر: MDPI AG, 2020.
سنة النشر: 2020
المجموعة: LCC:Veterinary medicine
LCC:Zoology
مصطلحات موضوعية: defatted rice bran, blood, intestinal mucosal, oxidative stress, finishing pigs, Veterinary medicine, SF600-1100, Zoology, QL1-991
الوصف: Rice bran is a waste product with low cost and high fiber content, giving it an added advantage over corn and soybean meal, which have to be purchased and always at a relatively higher cost. Under the background of increased attention to sustainable agriculture, it is significant to find alternative uses for this byproduct. A total of 35 finishing pigs were allotted to five dietary treatments: a control group with basal diet and four experimental diets where corn was equivalently substituted by 7%, 14%, 21%, and 28% defatted rice bran (DFRB), respectively. With increasing levels of DFRB, the neutrophil to lymphocyte ratio (NLR) linearly decreased (p < 0.05). In the jejunum, the mRNA level of nuclear factor erythroid-2 related factor-2 (Nrf2) exhibited a quadratic response (p < 0.01) with incremental levels of DFRB. In the colon, the mRNA levels of mucin 2 (MUC2), Nrf2, and NAD(P)H: quinone oxidoreductase 1 (NQO1) were upregulated (linear, p < 0.05) and heme oxygenase-1 (HO-1) was upregulated (linear, p < 0.01). Overall, using DFRB to replace corn decreased the inflammatory biomarkers of serum and showed potential function in modulating the intestinal barrier by upregulating the mRNA expression levels of MUC2 and downregulating that of Nrf2, NQO1, and HO-1 in the colon.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2076-2615
Relation: https://www.mdpi.com/2076-2615/10/3/449; https://doaj.org/toc/2076-2615
DOI: 10.3390/ani10030449
URL الوصول: https://doaj.org/article/ec8ad9a073f64c77a6e99695476e167d
رقم الانضمام: edsdoj.8ad9a073f64c77a6e99695476e167d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20762615
DOI:10.3390/ani10030449