Academic Journal
Hypoferremia is Associated With Increased Hospitalization and Oxygen Demand in COVID-19 Patients
| العنوان: | Hypoferremia is Associated With Increased Hospitalization and Oxygen Demand in COVID-19 Patients |
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| المؤلفون: | Theresa Hippchen, Sandro Altamura, Martina U. Muckenthaler, Uta Merle |
| المصدر: | HemaSphere, Vol 4, Iss 6, p e492 (2020) |
| بيانات النشر: | Wiley, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Diseases of the blood and blood-forming organs |
| مصطلحات موضوعية: | Diseases of the blood and blood-forming organs, RC633-647.5 |
| الوصف: | Abstract. Iron metabolism might play a crucial role in cytokine release syndrome in COVID-19 patients. Therefore, we assessed iron metabolism markers in COVID-19 patients for their ability to predict disease severity. COVID-19 patients referred to the Heidelberg University Hospital were retrospectively analyzed. Patients were divided into outpatients (cohort A, n = 204), inpatients (cohort B, n = 81), and outpatients later admitted to hospital because of health deterioration (cohort C, n = 23). Iron metabolism parameters were severely altered in patients of cohort B and C compared to cohort A. In multivariate regression analysis including age, gender, CRP and iron-related parameters only serum iron and ferritin were significantly associated with hospitalization. ROC analysis revealed an AUC for serum iron of 0.894 and an iron concentration |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2572-9241 00000000 |
| Relation: | http://journals.lww.com/10.1097/HS9.0000000000000492; https://doaj.org/toc/2572-9241 |
| DOI: | 10.1097/HS9.0000000000000492 |
| URL الوصول: | https://doaj.org/article/87d4d9452f8147a0b6500f0e6f5c7a28 |
| رقم الانضمام: | edsdoj.87d4d9452f8147a0b6500f0e6f5c7a28 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 25729241 00000000 |
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| DOI: | 10.1097/HS9.0000000000000492 |