Academic Journal

A study of various complications and outcome of falciparum malaria in patients of a rural South Indian medical college hospital

التفاصيل البيبلوغرافية
العنوان: A study of various complications and outcome of falciparum malaria in patients of a rural South Indian medical college hospital
المؤلفون: Nilam Kumari Singh, Chinta Rajkumar, Avin Subhash, M V Nagabhushana, Srinivasa Rao, G Nataral, Y J Visweswara Reddy
المصدر: Journal of Clinical and Scientific Research, Vol 6, Iss 2, Pp 129-132 (2017)
بيانات النشر: Wolters Kluwer Medknow Publications, 2017.
سنة النشر: 2017
المجموعة: LCC:Medicine
مصطلحات موضوعية: Medicine
الوصف: Background: Sparse published data are available regarding clinical presentation and complications of falciparum malaria from Andhra Pradesh state. Methods: In this prospective, observational study conducted during the period November 2012 to June 2014 at our teaching hospital in Kuppam, Andhra Pradesh, adult patients (n=96) admitted with fever confirmed to be suffering from falciparum malaria based on peripheral blood smear examination and / or malaria antigen test positive by rapid diagnostic test were studied. The clinical presentation and various complications of falciparum malaria were documented. Results: The male to female ratio was 2:1. Majority of the patients (70%) were in the age group 26-60 years. Fever was present in all cases. Splenomegaly (66%) was the most common physical sign followed by pallor (31%) and icterus (22%). Anaemia (51%), was the most common complication, followed by cerebral malaria (33.3%), acute respiratory distress syndrome (ARDS) (32.3%), acute kidney injury (AKI) (29.2%), and jaundice (25%). Majority of the patients presented with multiple complications (73%) than single complication (27%). Artemesinin-based combination therapy was administered to 72 of the 96 patients of whom 43 patients recovered. Quinine therapy was given to 14 patients of whom 10 recovered. Quinine plus ACT combination therapy was given to 10 patients and 7 recovered. seven of the 96 patients died; and 29 out of 96 patients were taken home against medical advice. Overall 36/96 (37.5%) patients had a poor outcome. All 7 patients who expired had multiple complications. Mortality was higher in patients who had co-existent AKI, hypotension and cerebral malaria. Conclusion: Early identification of high risk cases and institution of prompt treatment can reduce the mortality rate in falciparum malaria.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2277-5706
2277-8357
Relation: http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2017;volume=6;issue=2;spage=129;epage=132;aulast=Singh;type=0; https://doaj.org/toc/2277-5706; https://doaj.org/toc/2277-8357
DOI: 10.15380/2277-5706.JCSR.15.044
URL الوصول: https://doaj.org/article/c87c098c759840c8b8d05882a476b79a
رقم الانضمام: edsdoj.87c098c759840c8b8d05882a476b79a
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22775706
22778357
DOI:10.15380/2277-5706.JCSR.15.044