التفاصيل البيبلوغرافية
| العنوان: |
Frequency and predictors of estimated HIV transmissions and bacterial STI acquisition among HIV‐positive patients in HIV care across three continents |
| المؤلفون: |
Steven A Safren, James P Hughes, Matthew J Mimiaga, Ayana T Moore, Ruth Khalili Friedman, Kriengkrai Srithanaviboonchai, Mohammed Limbada, Brian D Williamson, Vanessa Elharrar, Vanessa Cummings, Jessica F Magidson, Charlotte A Gaydos, David D Celentano, Kenneth H Mayer, for the HPTN063 Study Team |
| المصدر: |
Journal of the International AIDS Society, Vol 19, Iss 1, Pp n/a-n/a (2016) |
| بيانات النشر: |
Wiley, 2016. |
| سنة النشر: |
2016 |
| المجموعة: |
LCC:Immunologic diseases. Allergy |
| مصطلحات موضوعية: |
treatment as prevention, secondary prevention, MSM, global HIV prevention, global HIV transmission, Immunologic diseases. Allergy, RC581-607 |
| الوصف: |
Introduction Successful global treatment as prevention (TasP) requires identifying HIV‐positive individuals at high risk for transmitting HIV, and having impact via potential infections averted. This study estimated the frequency and predictors of numbers of HIV transmissions and bacterial sexually transmitted infection (STI) acquisition among sexually active HIV‐positive individuals in care from three representative global settings. Methods HIV‐positive individuals (n=749), including heterosexual men, heterosexual women and men who have sex with men (MSM) in HIV care, were recruited from Chiang Mai (Thailand), Rio De Janeiro (Brazil) and Lusaka (Zambia). Participants were assessed on HIV and STI sexual transmission risk variables, psychosocial characteristics and bacterial STIs at enrolment and quarterly for 12 months (covering 15 months). Estimated numbers of HIV transmissions per person were calculated using reported numbers of partners and sex acts together with estimates of HIV transmissibility, accounting for ART treatment and condom use. Results An estimated 3.81 (standard error, (SE)=0.63) HIV transmissions occurred for every 100 participants over the 15 months, which decreased over time. The highest rate was 19.50 (SE=1.68) for every 100 MSM in Brazil. In a multivariable model, country×risk group interactions emerged: in Brazil, MSM had 2.85 (95% CI=1.45, 4.25, p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1758-2652 |
| Relation: |
https://doaj.org/toc/1758-2652 |
| DOI: |
10.7448/IAS.19.1.21096 |
| URL الوصول: |
https://doaj.org/article/87411ed8e4be4317a01e295876b581a5 |
| رقم الانضمام: |
edsdoj.87411ed8e4be4317a01e295876b581a5 |
| قاعدة البيانات: |
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