Academic Journal

Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway

التفاصيل البيبلوغرافية
العنوان: Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway
المؤلفون: Nesa Janamo Berenjabad, Vahid Nejati, Jafar Rezaie
المصدر: BMC Molecular and Cell Biology, Vol 23, Iss 1, Pp 1-10 (2022)
بيانات النشر: BMC, 2022.
سنة النشر: 2022
المجموعة: LCC:Cytology
مصطلحات موضوعية: Angiogenesis, HUVECs, H2O2, Age-related diseases, Senescence, Cytology, QH573-671
الوصف: Abstract Background Many attempts are used to discover mechanisms driving impaired angiogenesis in age-related diseases. Angiogenesis is highly regulated by different signaling pathways. Here, we investigated the angiogenesis potential of human endothelial cells (ECs) upon exposure to hydrogen peroxide (H2O2), a cellular senescent factor. Results Data showed that the wound healing rate of HUVECs decreased upon incubation with H2O2 (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2661-8850
Relation: https://doaj.org/toc/2661-8850
DOI: 10.1186/s12860-022-00435-4
URL الوصول: https://doaj.org/article/dd86f41ddddd4cd4af9cfc8ad3cb9cbc
رقم الانضمام: edsdoj.86f41ddddd4cd4af9cfc8ad3cb9cbc
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:26618850
DOI:10.1186/s12860-022-00435-4