التفاصيل البيبلوغرافية
العنوان: |
Psychotic symptoms in Chinese adolescent patients with major depressive disorder: prevalence and related endocrine clinical factors |
المؤلفون: |
Shiyu Sun, Wei Jin, Tianle Hou, Siyu Tong, Siyao Zhou, Lan Hong, Keqing Yao, Ke Zhao, Tiansheng Zheng |
المصدر: |
BMC Psychiatry, Vol 24, Iss 1, Pp 1-9 (2024) |
بيانات النشر: |
BMC, 2024. |
سنة النشر: |
2024 |
المجموعة: |
LCC:Psychiatry |
مصطلحات موضوعية: |
Major depressive disorder, Psychotic symptom, Prevalence, Prolactin, Thyroid hormones, Psychiatry, RC435-571 |
الوصف: |
Abstract Objective Major depressive disorder (MDD) is often accompanied by psychotic symptoms. However, few studies have examined the relationship between psychotic symptoms and endocrine factors in adolescent patients with MDD. Therefore, this study aimed to investigate the prevalence and related endocrine clinical factors of psychotic symptoms in Chinese adolescent patients with MDD. Methods In total, 601 patients (aged 12–18) with MDD were recruited. The Patient Health Questionnaire – 9 items (PHQ – 9) was utilized for assessing depressive symptoms. Psychotic symptoms were assessed through clinical interviews. Prolactin (PRL), thyroid-stimulating hormone (TSH), triiodothyronine (T3), free triiodothyronine (FT3), thyroxine (T4), and free thyroxine (FT4) were also measured. Results The incidence of psychotic symptoms in adolescent patients with MDD was 22.6%. The findings demonstrated that age, self-harming behavior, PHQ-9 score, FT4, and normalized PRL were independently associated with psychotic symptoms in patients with MDD (All p |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
1471-244X |
Relation: |
https://doaj.org/toc/1471-244X |
DOI: |
10.1186/s12888-024-06023-4 |
URL الوصول: |
https://doaj.org/article/8656de2202aa44c9a05c2fe81f3e198e |
رقم الانضمام: |
edsdoj.8656de2202aa44c9a05c2fe81f3e198e |
قاعدة البيانات: |
Directory of Open Access Journals |