Academic Journal

Psychotic symptoms in Chinese adolescent patients with major depressive disorder: prevalence and related endocrine clinical factors

التفاصيل البيبلوغرافية
العنوان: Psychotic symptoms in Chinese adolescent patients with major depressive disorder: prevalence and related endocrine clinical factors
المؤلفون: Shiyu Sun, Wei Jin, Tianle Hou, Siyu Tong, Siyao Zhou, Lan Hong, Keqing Yao, Ke Zhao, Tiansheng Zheng
المصدر: BMC Psychiatry, Vol 24, Iss 1, Pp 1-9 (2024)
بيانات النشر: BMC, 2024.
سنة النشر: 2024
المجموعة: LCC:Psychiatry
مصطلحات موضوعية: Major depressive disorder, Psychotic symptom, Prevalence, Prolactin, Thyroid hormones, Psychiatry, RC435-571
الوصف: Abstract Objective Major depressive disorder (MDD) is often accompanied by psychotic symptoms. However, few studies have examined the relationship between psychotic symptoms and endocrine factors in adolescent patients with MDD. Therefore, this study aimed to investigate the prevalence and related endocrine clinical factors of psychotic symptoms in Chinese adolescent patients with MDD. Methods In total, 601 patients (aged 12–18) with MDD were recruited. The Patient Health Questionnaire – 9 items (PHQ – 9) was utilized for assessing depressive symptoms. Psychotic symptoms were assessed through clinical interviews. Prolactin (PRL), thyroid-stimulating hormone (TSH), triiodothyronine (T3), free triiodothyronine (FT3), thyroxine (T4), and free thyroxine (FT4) were also measured. Results The incidence of psychotic symptoms in adolescent patients with MDD was 22.6%. The findings demonstrated that age, self-harming behavior, PHQ-9 score, FT4, and normalized PRL were independently associated with psychotic symptoms in patients with MDD (All p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-244X
Relation: https://doaj.org/toc/1471-244X
DOI: 10.1186/s12888-024-06023-4
URL الوصول: https://doaj.org/article/8656de2202aa44c9a05c2fe81f3e198e
رقم الانضمام: edsdoj.8656de2202aa44c9a05c2fe81f3e198e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1471244X
DOI:10.1186/s12888-024-06023-4