التفاصيل البيبلوغرافية
| العنوان: |
Multiparametric quantification and visualization of liver fat using ultrasound |
| المؤلفون: |
Jihye Baek, Ahmed El Kaffas, Aya Kamaya, Kenneth Hoyt, Kevin J. Parker |
| المصدر: |
WFUMB Ultrasound Open, Vol 2, Iss 1, Pp 100045- (2024) |
| بيانات النشر: |
Elsevier, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Medical technology |
| مصطلحات موضوعية: |
Human steatosis, Multiparametric analysis, H-scan, Fat quantification imaging, Medical technology, R855-855.5 |
| الوصف: |
Objectives: Several ultrasound measures have shown promise for assessment of steatosis compared to traditional B-scan, however clinicians may be required to integrate information across the parameters. Here, we propose an integrated multiparametric approach, enabling simple clinical assessment of key information from combined ultrasound parameters. Methods: We have measured 13 parameters related to ultrasound and shear wave elastography. These were measured in 30 human subjects under a study of liver fat. The 13 individual measures are assessed for their predictive value using independent magnetic resonance imaging-derived proton density fat fraction (MRI-PDFF) measurements as a reference standard. In addition, a comprehensive and fine-grain analysis is made of all possible combinations of sub-sets of these parameters to determine if any subset can be efficiently combined to predict fat fraction. Results: We found that as few as four key parameters related to ultrasound propagation are sufficient to generate a linear multiparametric parameter with a correlation against MRI-PDFF values of greater than 0.93. This optimal combination was found to have a classification area under the curve (AUC) approaching 1.0 when applying a threshold for separating steatosis grade zero from higher classes. Furthermore, a strategy is developed for applying local estimates of fat content as a color overlay to produce a visual impression of the extent and distribution of fat within the liver. Conclusion: In principle, this approach can be applied to most clinical ultrasound systems to provide the clinician and patient with a rapid and inexpensive estimate of liver fat content. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2949-6683 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2949668324000132; https://doaj.org/toc/2949-6683 |
| DOI: |
10.1016/j.wfumbo.2024.100045 |
| URL الوصول: |
https://doaj.org/article/85099b0af1964c56a750649c648822ef |
| رقم الانضمام: |
edsdoj.85099b0af1964c56a750649c648822ef |
| قاعدة البيانات: |
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