Academic Journal
Prevalence, incidence of and risk factors for vertebral fracture in the community: the Vietnam Osteoporosis Study
| العنوان: | Prevalence, incidence of and risk factors for vertebral fracture in the community: the Vietnam Osteoporosis Study |
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| المؤلفون: | Hoa T. Nguyen, Bao T. Nguyen, Thi H. Nhung Thai, An V. Tran, Tan T. Nguyen, Tam Vo, Linh D. Mai, Thach S. Tran, Tuan V. Nguyen, Lan T. Ho-Pham |
| المصدر: | Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024) |
| بيانات النشر: | Nature Portfolio, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | Abstract The epidemiology of vertebral fractures (VF) in underrepresented populations is not well-documented. This cohort study was part of a longitudinal osteoporosis research project with the aim of determining the prevalence, incidence, and risk factors for VF. 401 individuals (155 men) aged 50 years and older without a clinical diagnosis of VF were took radiographs at baseline and 2 years later. VF were ascertained using the Genant's semi-quantitative method. Bone mineral density (BMD) of femoral neck and lumbar spine were measured by dual-energy X-ray absorptiometry (Hologic Inc). The association between VF and risk factors was analyzed by the multiple logistic regression. The 95% confidence interval for prevalence and incidence was estimated by exact Poisson test. At baseline, the prevalence of VF was 12.2% (n = 49, 95% CI 9.0–16.2%) and increased with advancing age with one-fifth of those aged 70 and older having a VF. During the follow-up period, we observed 6 new VF, making the incidence of 6.6/1000 person-years (n = 6, 95% CI 2.4–14.3). The risk of prevalent VF was associated with male gender (OR: 2.67; 95% CI 1.28–5.87) and T-score at the femoral neck (OR per one SD decrease: 1.1; 1.03–1.17). These data indicate that VF is common among adults, and that lower femoral neck BMD was a risk factor for VF. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-023-50145-w |
| URL الوصول: | https://doaj.org/article/a84df7b54c634b33b6557e213789d558 |
| رقم الانضمام: | edsdoj.84df7b54c634b33b6557e213789d558 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20452322 |
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| DOI: | 10.1038/s41598-023-50145-w |