التفاصيل البيبلوغرافية
| العنوان: |
Synthesis and Characterization of Novel Heterocyclic Chalcones from 1-Phenyl-1H-pyrazol-3-ol |
| المؤلفون: |
Arminas Urbonavičius, Graziana Fortunato, Emilija Ambrazaitytė, Elena Plytninkienė, Aurimas Bieliauskas, Vaida Milišiūnaitė, Renzo Luisi, Eglė Arbačiauskienė, Sonata Krikštolaitytė, Algirdas Šačkus |
| المصدر: |
Molecules, Vol 27, Iss 12, p 3752 (2022) |
| بيانات النشر: |
MDPI AG, 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Organic chemistry |
| مصطلحات موضوعية: |
Claisen–Schmidt condensation, heterocyclic chalcones, pyrazole, pyridine, 1,2-oxazole (isoxazole), 15N-labeled 1,2-oxazole, Organic chemistry, QD241-441 |
| الوصف: |
An efficient synthetic route to construct diverse pyrazole-based chalcones from 1-phenyl-1H-pyrazol-3-ols bearing a formyl or acetyl group on the C4 position of pyrazole ring, employing a base-catalysed Claisen–Schmidt condensation reaction, is described. Isomeric chalcones were further reacted with N-hydroxy-4-toluenesulfonamide and regioselective formation of 3,5-disubstituted 1,2-oxazoles was established. The novel pyrazole-chalcones and 1,2-oxazoles were characterized by an in-depth analysis of NMR spectral data, which were obtained through a combination of standard and advanced NMR spectroscopy techniques. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1420-3049 |
| Relation: |
https://www.mdpi.com/1420-3049/27/12/3752; https://doaj.org/toc/1420-3049 |
| DOI: |
10.3390/molecules27123752 |
| URL الوصول: |
https://doaj.org/article/c84d84da98184c89b99e1347f796afa6 |
| رقم الانضمام: |
edsdoj.84d84da98184c89b99e1347f796afa6 |
| قاعدة البيانات: |
Directory of Open Access Journals |
Full Text Finder