التفاصيل البيبلوغرافية
| العنوان: |
Differentiating Multisystem Inflammatory Syndrome in Children from Kawasaki Disease During the Pandemic |
| المؤلفون: |
Seher Şener, Ezgi Deniz Batu, Ümmüşen Kaya Akca, Erdal Atalay, Müşerref Kasap Cüceoğlu, Zeynep Balık, Özge Başaran, Tevfik Karagöz, Yasemin Özsürekçi, Yelda Bilginer, Seza Özen |
| المصدر: |
Turkish Archives of Pediatrics, Vol 59, Iss 2, Pp 150-156 (2024) |
| بيانات النشر: |
AVES Yayincilik, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Pediatrics |
| مصطلحات موضوعية: |
Pediatrics, RJ1-570 |
| الوصف: |
Objective: We aimed to delineate the distinctive characteristics that aid in distinguishing between Kawasaki disease (KD) and multisystem inflammatory syndrome in children (MIS-C) with KD-like manifestations during the pandemic. Materials and Methods: We evaluated KD patients and MIS-C patients with KD-like symptoms admitted during the pandemic (between January 2021 and December 2022). Results: Thirty-three MIS-C patients and 15 KD patients were included. Kawasaki disease patients were younger than MIS-C patients (3.4 vs. 7.6 years). Rash (P = .044, 100% vs. 75.7%), oral mucosal changes (P = .044, 100% vs. 75.7%), and cervical lymphadenopathy (P = .001, 93.3% vs. 42.4%) were more common in KD. Multisystem inflammatory syndrome in children: patients had more hypotension (P = .002, 45.4% vs. 0), gastrointestinal (P < .001, 72.7% vs. 13.3%), and respiratory symptoms (P = .044, 24.2% vs. 0). Multisystem inflammatory syndrome in children patients also had low lymphocyte and thrombocyte counts and elevated levels of d-dimer, ferritin, and cardiac parameters, unlike KD patients. Multisystem inflammatory syndrome in children patients exhibited a notable reduction in left ventricular systolic function in echocardiography. Another significant difference with regard to management was the anakinra treatment, which was prescribed for MIS-C patients. Conclusion: Although MIS-C patients might display a clinical resemblance to KD, several features could help differentiate between MIS-C and classical KD. Specific clinical (hypotension, gastrointestinal, and respiratory symptoms) and laboratory (low lymphocyte and thrombocyte counts with higher C-reactive protein, ferritin, d-dimer, and cardiac parameters) features are characteristic of MIS-C. In addition, divergence in management strategies is evident between the 2 diseases, as biologic drugs were more prevalently employed in MIS-C patients than in classical KD patients. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2757-6256 |
| Relation: |
https://turkarchpediatr.org/en/differentiating-multisystem-inflammatory-syndrome-in-children-from-kawasaki-disease-during-the-pandemic-131637; https://doaj.org/toc/2757-6256 |
| DOI: |
10.5152/TurkArchPediatr.2024.23192 |
| URL الوصول: |
https://doaj.org/article/d8472a069a944d4395c4888d03671a43 |
| رقم الانضمام: |
edsdoj.8472a069a944d4395c4888d03671a43 |
| قاعدة البيانات: |
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