Academic Journal

Targeting gut microbiota and metabolism profiles with coated sodium butyrate to ameliorate high-energy and low-protein diet-induced intestinal barrier dysfunction in laying hens

التفاصيل البيبلوغرافية
العنوان: Targeting gut microbiota and metabolism profiles with coated sodium butyrate to ameliorate high-energy and low-protein diet-induced intestinal barrier dysfunction in laying hens
المؤلفون: Sasa Miao, Jiankui Li, Ying Chen, Wenyan Zhao, Mengru Xu, Fang Liu, Xiaoting Zou, Xinyang Dong
المصدر: Animal Nutrition, Vol 19, Iss , Pp 104-116 (2024)
بيانات النشر: KeAi Communications Co., Ltd., 2024.
سنة النشر: 2024
المجموعة: LCC:Animal culture
مصطلحات موضوعية: Coated sodium butyrate, Intestinal barrier, High-energy and low-protein, Gut microbiota, Laying hen, Animal culture, SF1-1100
الوصف: High energy diets are a risk factor for intestinal barrier damage. Butyrate, a major energy source for intestinal epithelial cells, has been shown to improve barrier dysfunction and modulate the gut microbiota. In this trial, we examined the preventative effect of coated sodium butyrate (CSB) on high-energy and low-protein (HELP)-induced intestinal barrier injury in laying hens, and also worked to determine the underlying mechanisms by an integrative analysis of gut microbiota and the metabolome. A total of 216 healthy 28-week-old Huafeng laying hens were randomly assigned to 3 groups with 6 replicates each: the CON group (normal diet), HELP group (HELP diet) and CH500 group (500 mg/kg CSB added to HELP diet). The duration of the trial encompassed a period of 10 weeks. The results revealed that CSB treatment improved the laying rate and mitigated the detrimental effects on intestinal barrier function and the inflammatory response induced by the HELP diet in laying hens (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2405-6545
Relation: http://www.sciencedirect.com/science/article/pii/S2405654524001021; https://doaj.org/toc/2405-6545
DOI: 10.1016/j.aninu.2024.06.006
URL الوصول: https://doaj.org/article/83ca1b55a9e54b55b61db5aca59b868d
رقم الانضمام: edsdoj.83ca1b55a9e54b55b61db5aca59b868d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:24056545
DOI:10.1016/j.aninu.2024.06.006