التفاصيل البيبلوغرافية
| العنوان: |
Automated Quantification of Abnormal QRS Peaks From High‐Resolution ECGs Predicts Late Ventricular Arrhythmias in Hypertrophic Cardiomyopathy: A 5‐Year Prospective Multicenter Study |
| المؤلفون: |
Adrian M. Suszko, Praloy Chakraborty, Karthik Viswanathan, Scott Barichello, John Sapp, Mario Talajic, Zachary Laksman, Raymond Yee, Anna Woo, Danna Spears, Arnon Adler, Harry Rakowski, Vijay S. Chauhan |
| المصدر: |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 23 (2022) |
| بيانات النشر: |
Wiley, 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: |
hypertrophic cardiomyopathy, myocardial disarray, QRS fractionation, risk stratification, sudden cardiac death, ventricular arrhythmias, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: |
Background Patients with hypertrophic cardiomyopathy (HCM) are at risk of ventricular arrhythmia (VA) attributed to abnormal electrical activation arising from myocardial fibrosis and myocyte disarray. We sought to quantify intra‐QRS peaks (QRSp) in high‐resolution ECGs as a measure of abnormal activation to predict late VA in patients with HCM. Methods and Results Prospectively enrolled patients with HCM (n=143, age 53±14 years) with prophylactic implantable cardioverter‐defibrillators had 3‐minute, high‐resolution (1024 Hz), digital 12‐lead ECGs recorded during intrinsic rhythm. For each precordial lead, QRSp was defined as the total number of peaks detected in the QRS complex that deviated from a smoothing filtered version of the QRS. The VA end point was appropriate implantable cardioverter‐defibrillator therapy during 5‐year prospective follow‐up. After 5 years, 21 (16%) patients had VA. Patients who were VA positive had greater QRSp (6.0 [4.0–7.0] versus 4.0 [2.0–5.0]; P |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2047-9980 |
| Relation: |
https://doaj.org/toc/2047-9980 |
| DOI: |
10.1161/JAHA.122.026025 |
| URL الوصول: |
https://doaj.org/article/ee83c9ae18c1409d959b4e5f3a31d477 |
| رقم الانضمام: |
edsdoj.83c9ae18c1409d959b4e5f3a31d477 |
| قاعدة البيانات: |
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