Academic Journal
A novel strain of Leishmania braziliensis harbors not a toti- but a bunyavirus.
| العنوان: | A novel strain of Leishmania braziliensis harbors not a toti- but a bunyavirus. |
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| المؤلفون: | Alexei Yu Kostygov, Danyil Grybchuk, Senne Heeren, Evgeny S Gerasimov, Donnamae Klocek, Aditya Reddy, Jovana Sádlová, Lenka Pacáková, Alain Kohl, František Stejskal, Petr Volf, Jean-Claude Dujardin, Vyacheslav Yurchenko |
| المصدر: | PLoS Neglected Tropical Diseases, Vol 18, Iss 12, p e0012767 (2024) |
| بيانات النشر: | Public Library of Science (PLoS), 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Arctic medicine. Tropical medicine LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270 |
| الوصف: | Leishmania is a genus of the family Trypanosomatidae that unites obligatory parasitic flagellates causing a variety of vector-borne diseases collectively called leishmaniasis. The symptoms range from relatively innocuous skin lesions to complete failures of visceral organs. The disease is exacerbated if a parasite harbors Leishmania RNA viruses (LRVs) of the family Pseudototiviridae. Screening a novel isolate of L. braziliensis, we revealed that it possesses not a toti-, but a bunyavirus of the family Leishbuviridae. To the best of our knowledge, this is a very first discovery of a bunyavirus infecting a representative of the Leishmania subgenus Viannia. We suggest that these viruses may serve as potential factors of virulence in American leishmaniasis and encourage researchers to test leishmanial strains for the presence of not only LRVs, but also other RNA viruses. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1935-2727 1935-2735 |
| Relation: | https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735 |
| DOI: | 10.1371/journal.pntd.0012767 |
| URL الوصول: | https://doaj.org/article/83c18bf8086f4b18a2f3a0fca1b17749 |
| رقم الانضمام: | edsdoj.83c18bf8086f4b18a2f3a0fca1b17749 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19352727 19352735 |
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| DOI: | 10.1371/journal.pntd.0012767 |