Academic Journal

Association between tumor-infiltrating lymphocytes and survival in patients with metastatic breast cancer receiving first-line chemotherapy: analysis of CALGB 40502

التفاصيل البيبلوغرافية
العنوان: Association between tumor-infiltrating lymphocytes and survival in patients with metastatic breast cancer receiving first-line chemotherapy: analysis of CALGB 40502
المؤلفون: Daniel G. Stover, Roberto Salgado, Oleksander Savenkov, Karla Ballman, Erica L. Mayer, Mark Jesus M. Magbanua, Sherene Loi, Mark Vater, Kristyn Glover, Mark Watson, Yujia Wen, W. Fraser Symmans, Charles Perou, Lisa A. Carey, Ann H. Partridge, Hope S. Rugo
المصدر: npj Breast Cancer, Vol 10, Iss 1, Pp 1-5 (2024)
بيانات النشر: Nature Portfolio, 2024.
سنة النشر: 2024
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Abstract Association of stromal tumor-infiltrating lymphocytes (sTILs) with survival outcomes among patients with metastatic breast cancer (MBC) remains unclear. The primary objective was to evaluate the association of sTILs with progression-free survival in randomized phase III trial CALGB 40502. sTILs were associated with progression-free and overall survival in chemotherapy-treated MBC when controlling for treatment arm; however, this effect did not remain significant after additional adjustment for hormone receptor status. CALGB is now part of the Alliance for Clinical Trials in Oncology. Trial Registration: ClinicalTrials.gov: NCT00785291.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2374-4677
Relation: https://doaj.org/toc/2374-4677
DOI: 10.1038/s41523-024-00683-x
URL الوصول: https://doaj.org/article/83a9a621c06f4389a3a50e11d37a5714
رقم الانضمام: edsdoj.83a9a621c06f4389a3a50e11d37a5714
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23744677
DOI:10.1038/s41523-024-00683-x