التفاصيل البيبلوغرافية
العنوان: |
Association between tumor-infiltrating lymphocytes and survival in patients with metastatic breast cancer receiving first-line chemotherapy: analysis of CALGB 40502 |
المؤلفون: |
Daniel G. Stover, Roberto Salgado, Oleksander Savenkov, Karla Ballman, Erica L. Mayer, Mark Jesus M. Magbanua, Sherene Loi, Mark Vater, Kristyn Glover, Mark Watson, Yujia Wen, W. Fraser Symmans, Charles Perou, Lisa A. Carey, Ann H. Partridge, Hope S. Rugo |
المصدر: |
npj Breast Cancer, Vol 10, Iss 1, Pp 1-5 (2024) |
بيانات النشر: |
Nature Portfolio, 2024. |
سنة النشر: |
2024 |
المجموعة: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: |
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: |
Abstract Association of stromal tumor-infiltrating lymphocytes (sTILs) with survival outcomes among patients with metastatic breast cancer (MBC) remains unclear. The primary objective was to evaluate the association of sTILs with progression-free survival in randomized phase III trial CALGB 40502. sTILs were associated with progression-free and overall survival in chemotherapy-treated MBC when controlling for treatment arm; however, this effect did not remain significant after additional adjustment for hormone receptor status. CALGB is now part of the Alliance for Clinical Trials in Oncology. Trial Registration: ClinicalTrials.gov: NCT00785291. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2374-4677 |
Relation: |
https://doaj.org/toc/2374-4677 |
DOI: |
10.1038/s41523-024-00683-x |
URL الوصول: |
https://doaj.org/article/83a9a621c06f4389a3a50e11d37a5714 |
رقم الانضمام: |
edsdoj.83a9a621c06f4389a3a50e11d37a5714 |
قاعدة البيانات: |
Directory of Open Access Journals |