Academic Journal
Anaplastic Pilocytic Astrocytoma in adults: A comprehensive literature review based on 2 clinical cases
| العنوان: | Anaplastic Pilocytic Astrocytoma in adults: A comprehensive literature review based on 2 clinical cases |
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| المؤلفون: | Pedro Miguel González – Vargas, M.D., Lourdes Calero Félix, M.D., José Luis Thenier-Villa, M.D., PhD., Antía Domínguez Núñez, M.D., Adolfo de la Lama Zaragoza, M.D., Cesáreo Conde Alonso, M.D., PhD. |
| المصدر: | Interdisciplinary Neurosurgery, Vol 25, Iss , Pp 101141- (2021) |
| بيانات النشر: | Elsevier, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Surgery LCC:Neurology. Diseases of the nervous system |
| مصطلحات موضوعية: | Astrocytoma, Anaplastic, Pilocytic, Prognostic surgery, Surgery, RD1-811, Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | Anaplastic Pilocytic Astrocytoma (APA) is a subtype of Pilocytic Astrocytoma (PA) that appears when the tumor shows signs of anaplasia and follow an aggressive clinical course. It is a very rarely tumor, especially in older than 18 years. We made a screening of our data base to find patients who was discharged with the diagnostic of APA and we made a search in PubMed to find articles that represents this kind of tumors and realize a literature review. We present 2 cases of patients with APA diagnostic: a progression from a Pilocytic Astrocytoma in a 38 years-old woman and a 36 years-old woman with a cerebellar APA. Both patients were operated without complications and persist asymptomatic in a five- and seven-years follow-up. On the literature review we found 18 articles with a total of 84 patients and described demographic, clinical, radiological, histopathological and genetic features. To our knowledge, the pathological presentation behavior of our clinical cases is very rare and can contribute important data to the published literature.APA is more aggressive than classical PA. It is important to identify this variant for stablish the best and faster treatment options, adjuvant therapies, appropriate prognosis and active follow-up. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2214-7519 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2214751921000530; https://doaj.org/toc/2214-7519 |
| DOI: | 10.1016/j.inat.2021.101141 |
| URL الوصول: | https://doaj.org/article/cd837bea8b574060a330850897269c1d |
| رقم الانضمام: | edsdoj.837bea8b574060a330850897269c1d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22147519 |
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| DOI: | 10.1016/j.inat.2021.101141 |