Academic Journal
High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis
العنوان: | High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis |
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المؤلفون: | Guoshun Zhang, Bin Liu, Hua Shang, Guikai Wu, Diyang Wu, Liuqing Wang, Shengnan Li, Zhiyuan Wang, Suying Wang, Juxiang Yuan |
المصدر: | BMC Medical Genomics, Vol 15, Iss 1, Pp 1-11 (2022) |
بيانات النشر: | BMC, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Internal medicine LCC:Genetics |
مصطلحات موضوعية: | SRSF9, Hepatocellular carcinoma, Biomarkers, cg06116271, Prognosis, Internal medicine, RC31-1245, Genetics, QH426-470 |
الوصف: | Highlights SRSF9 is a potential independent risk factor for HCC. High methylation status of cg06116271 predicted a better prognosis in HCC. SRSF9 knockdown inhibited the Wnt signaling pathway and cell cycle pathway. SRSF9 may serve as a potential therapeutic target for HCC. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1755-8794 |
Relation: | https://doaj.org/toc/1755-8794 |
DOI: | 10.1186/s12920-022-01316-7 |
URL الوصول: | https://doaj.org/article/82d0ce5fcc634b2b8a87205884584b47 |
رقم الانضمام: | edsdoj.82d0ce5fcc634b2b8a87205884584b47 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 17558794 |
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DOI: | 10.1186/s12920-022-01316-7 |