التفاصيل البيبلوغرافية
| العنوان: |
Modifications on the Basic Skeletons of Vinblastine and Vincristine |
| المؤلفون: |
Csaba Szántay, György Kalaus, László Hazai, Péter Keglevich |
| المصدر: |
Molecules, Vol 17, Iss 5, Pp 5893-5914 (2012) |
| بيانات النشر: |
MDPI AG, 2012. |
| سنة النشر: |
2012 |
| المجموعة: |
LCC:Organic chemistry |
| مصطلحات موضوعية: |
antitumor therapy, vinblastine, vincristine, derivatives, Organic chemistry, QD241-441 |
| الوصف: |
The synthetic investigation of biologically active natural compounds serves two main purposes: (i) the total synthesis of alkaloids and their analogues; (ii) modification of the structures for producing more selective, more effective, or less toxic derivatives. In the chemistry of dimeric Vinca alkaloids enormous efforts have been directed towards synthesizing new derivatives of the antitumor agents vinblastine and vincristine so as to obtain novel compounds with improved therapeutic properties. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1420-3049 |
| Relation: |
http://www.mdpi.com/1420-3049/17/5/5893; https://doaj.org/toc/1420-3049 |
| DOI: |
10.3390/molecules17055893 |
| URL الوصول: |
https://doaj.org/article/a81c730409fe4158aa3b624c4191cc86 |
| رقم الانضمام: |
edsdoj.81c730409fe4158aa3b624c4191cc86 |
| قاعدة البيانات: |
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