التفاصيل البيبلوغرافية
| العنوان: |
Skeletal muscle mass is associated with erythropoietin response in hemodialysis patients |
| المؤلفون: |
Tomoaki Takata, Yukari Mae, Kentaro Yamada, Sosuke Taniguchi, Shintaro Hamada, Marie Yamamoto, Takuji Iyama, Hajime Isomoto |
| المصدر: |
BMC Nephrology, Vol 22, Iss 1, Pp 1-6 (2021) |
| بيانات النشر: |
BMC, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: |
ESA, Hyporesponsiveness, anemia, Muscle wasting, Sarcopenia, Resistance, Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: |
Abstract Background Hyporesponsiveness to erythropoietin stimulating agent (ESA) is associated with poor outcomes in patients with chronic kidney disease. Although ESA hyporesponsiveness and sarcopenia have a common pathophysiological background, clinical evidence linking them is scarce. The purpose of the study was to investigate the relationship between ESA responsiveness and skeletal muscle mass in hemodialysis patients. Methods This cross-sectional study analyzed 70 patients on maintenance hemodialysis who were treated with ESA. ESA responsiveness was evaluated by erythropoietin resistance index (ERI), calculated as a weekly dose of ESA divided by body weight and hemoglobin (IU/kg/week/dL), and a weekly dose of ESA/hemoglobin (IU/week/dL). A dose of ESA is equivalated to epoetin β. Correlations between ESA responsiveness and clinical parameters including skeletal muscle mass were analyzed. Results Among the 70 patients, ERI was positively correlated to age (p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1471-2369 |
| Relation: |
https://doaj.org/toc/1471-2369 |
| DOI: |
10.1186/s12882-021-02346-6 |
| URL الوصول: |
https://doaj.org/article/810ac1d5b1a34e61b43fbc9d88096a9f |
| رقم الانضمام: |
edsdoj.810ac1d5b1a34e61b43fbc9d88096a9f |
| قاعدة البيانات: |
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