Academic Journal

Appetite in Palliative Cancer Patients and Its Association with Albumin, CRP and Quality of Life in Men and Women—Cross-Sectional Data from the Palliative D-Study

التفاصيل البيبلوغرافية
العنوان: Appetite in Palliative Cancer Patients and Its Association with Albumin, CRP and Quality of Life in Men and Women—Cross-Sectional Data from the Palliative D-Study
المؤلفون: Charlotte Goodrose-Flores, Stephanie Bonn, Caritha Klasson, Maria Helde Frankling, Ylva Trolle Lagerros, Linda Björkhem-Bergman
المصدر: Life, Vol 12, Iss 5, p 671 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Science
مصطلحات موضوعية: cancer, palliative care, appetite, quality of life, sex differences, pain, Science
الوصف: Albumin is an important biochemical marker in palliative cancer care, used for assessment of nutritional status, disease severity and prognosis. Our primary aim was to investigate sex differences in the association between appetite and albumin levels in palliative cancer patients. We also aimed to study associations between appetite and C-reactive protein (CRP), Quality of Life (QoL), pain and fatigue. In the Palliative D-cohort, consisting of 266 men and 264 women, we found a correlation between appetite and albumin; low appetite, measured with the Edmonton Symptom Assessment System, correlated significantly with low albumin in men: (r = −0.33, p < 0.001), but not in women (r = −0.03, p = 0.65). In a regression analysis adjusted for confounding factors, results were similar. Lower appetite was correlated with higher CRP in men (r = 0.27, p < 0.001), but not in women (r = 0.12, p = 0.05). Appetite was correlated with QoL, fatigue and pain in both men and women; those with a low appetite had a low QoL and high fatigue- and pain-scores (p < 0.001). In conclusion, our results indicated possible sex differences in the associations between appetite and albumin, and between appetite and CRP, in palliative care patients. Understanding these associations could provide additional value for clinical practice.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2075-1729
Relation: https://www.mdpi.com/2075-1729/12/5/671; https://doaj.org/toc/2075-1729
DOI: 10.3390/life12050671
URL الوصول: https://doaj.org/article/c7e6a008b7c74b76852ad0eacc90d059
رقم الانضمام: edsdoj.7e6a008b7c74b76852ad0eacc90d059
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20751729
DOI:10.3390/life12050671