Academic Journal

Evaluation of the antibacterial effect of hydroalcoholic extract of the galls of Quercus infectoria on Aggregatibacter actinomycetemcomitans

التفاصيل البيبلوغرافية
العنوان: Evaluation of the antibacterial effect of hydroalcoholic extract of the galls of Quercus infectoria on Aggregatibacter actinomycetemcomitans
المؤلفون: Zohreh Tabibzadeh Noori, Mohadese Tabatabaei Rad, Mojdeh Hakemi Vala, Mehrdad Karimi, Azadeh Esmaeil Nejad
المصدر: Journal of Advanced Periodontology and Implant Dentistry, Vol 15, Iss 1, Pp 35-41 (2023)
بيانات النشر: Tabriz University of Medical Sciences, 2023.
سنة النشر: 2023
المجموعة: LCC:Dentistry
مصطلحات موضوعية: aggregatibacter actinomycetemcomitans, minimum bactericidal concentration, minimum inhibitory concentration, quercus infectoria, Dentistry, RK1-715
الوصف: Background. Aggregatibacter actinomycetemcomitans (Aa) plays a vital role in some destructive forms of periodontitis. While mechanical and chemical plaque control is the first step in periodontitis treatment, side effects of adjunctive chemical agents such as chlorhexidine (CHX) mouthwash have led to the application of natural alternatives with minimal side effects. Therefore, this study evaluated the antibacterial effect of the hydroalcoholic extract of Quercus infectoria (Qi) galls on Aa in vitro. Methods. The hydroalcoholic extract of Qi was obtained by the maceration method, and Aa bacterial strain was cultured. The inhibition zone diameter was measured through the agar well diffusion method. Also, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values were determined by the broth microdilution method. All the experiments were repeated three times. 0.2% CHX was used as a control. Results. The inhibition zone diameter of Aa increased with increasing concentration of Qi extract. While MIC and MBC values for CHX were 0.0039 and 0.0078 mg/mL, respectively, both MIC and MBC values of the Qi extract for this bacterium were similar, i.e., 2.5 mg/mL, which was significantly higherd. Conclusion. Since other in vivo studies have confirmed the other properties of this extract and its safety in terms of cytotoxicity and mutagenicity, hydroalcoholic extract of Qi may be used in mouthwashes or local delivery systems to affect periodontal biofilm.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2645-5390
Relation: https://japid.tbzmed.ac.ir/PDF/japid-15-35.pdf; https://doaj.org/toc/2645-5390
DOI: 10.34172/japid.2023.006
URL الوصول: https://doaj.org/article/7e42779475ef42cdaf916a0e18ee9467
رقم الانضمام: edsdoj.7e42779475ef42cdaf916a0e18ee9467
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:26455390
DOI:10.34172/japid.2023.006