Academic Journal

TheU-shape association between on-admission resting heart rate and 60-day all-cause mortality of AIDS inpatients in Fujian China: a retrospective cohort study

التفاصيل البيبلوغرافية
العنوان: TheU-shape association between on-admission resting heart rate and 60-day all-cause mortality of AIDS inpatients in Fujian China: a retrospective cohort study
المؤلفون: Rui Huang, Yan Li, Ling Chen, Yan Yang, Jinxiu Wang, Huan Zhao, Lifen Han
المصدر: AIDS Research and Therapy, Vol 21, Iss 1, Pp 1-8 (2024)
بيانات النشر: BMC, 2024.
سنة النشر: 2024
المجموعة: LCC:Immunologic diseases. Allergy
مصطلحات موضوعية: Resting heart rate, AIDS, Mortality, U-shape relationship, Immunologic diseases. Allergy, RC581-607
الوصف: Abstract Background An elevated resting heart rate (RHR) is associated with poor outcomes in both healthy individuals and those with human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS). This study aimed to investigated the association between on admission resting heart rate (RHR) and 60-day mortality. Methods This single-center retrospective cohort study evaluated the effect of RHR on the 60-day mortality of patient with AIDS in Southeast China. A total of 2188 patients with AIDS admitted for the first time between January 2016 and December 2021 were included. The RHR was categorized into tertiles. Disease progression was estimated using 60-day mortality rates. Cox proportional hazards regression models were used to evaluate the RHR with disease progression, and a two-piecewise Cox regression model was used to reveal the RHR effect at admission on 60-day mortality. Results We observed a U-shape relationship between RHR and 60-day mortality. For a above 90 bpm, the 60-day mortality rose rapidly with a multivariable adjusted odds ratio (OR) of 1.032 (95% confidence interval [CI 1.016–1.048, P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1742-6405
Relation: https://doaj.org/toc/1742-6405
DOI: 10.1186/s12981-024-00678-5
URL الوصول: https://doaj.org/article/e7e00ffba7774406bd7c17a7ae22ac47
رقم الانضمام: edsdoj.7e00ffba7774406bd7c17a7ae22ac47
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17426405
DOI:10.1186/s12981-024-00678-5