Academic Journal

New Lipophilic Piceatannol Derivatives Exhibiting Antioxidant Activity Prepared by Aromatic Hydroxylation with 2-Iodoxybenzoic Acid (IBX)

التفاصيل البيبلوغرافية
العنوان: New Lipophilic Piceatannol Derivatives Exhibiting Antioxidant Activity Prepared by Aromatic Hydroxylation with 2-Iodoxybenzoic Acid (IBX)
المؤلفون: Roberta Bernini, Carmela Spatafora, Maurizio Barontini
المصدر: Molecules, Vol 14, Iss 11, Pp 4669-4681 (2009)
بيانات النشر: MDPI AG, 2009.
سنة النشر: 2009
المجموعة: LCC:Organic chemistry
مصطلحات موضوعية: aromatic hydroxylation, 2-iodoxybenzoic acid (IBX), lipophilic piceatannol derivatives, lipophilic antioxidants, Organic chemistry, QD241-441
الوصف: Piceatannol (E-3,5,3’,4’-tetrahydroxystilbene) is a phytoalexin synthesized in grapes in response to stress conditions. It exhibits strong antioxidant and antileukaemic activities due to the presence of the catechol moiety. To modify some physical properties like solubility, and miscibility in non-aqueous media some new previously unreported piceatannol derivatives having lipophilic chains on the A-ring were prepared in good yields by a simple and efficient procedure. The key step was a chemo- and regioselective aromatic hydroxylation with 2-iodoxybenzoic acid (IBX). The new compounds showed antioxidant activity and seemed promising for possible applications as multifunctional emulsifiers in food, cosmetic and pharmaceutical fields.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1420-3049
Relation: http://www.mdpi.com/1420-3049/14/11/4669/; https://doaj.org/toc/1420-3049
DOI: 10.3390/molecules14114669
URL الوصول: https://doaj.org/article/7c4807aa5b7940f0851dca058c002320
رقم الانضمام: edsdoj.7c4807aa5b7940f0851dca058c002320
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14203049
DOI:10.3390/molecules14114669