التفاصيل البيبلوغرافية
| العنوان: |
Gustatory and olfactory dysfunctions in hospitalised patients with COVID-19 pneumonia: a prospective study |
| المؤلفون: |
Felipe García, Ana González Cordón, Pedro Puerta-Alcalde, Celia Cardozo, Carolina Garcia-Vidal, Marta Bodro, Isam Alobid, Juan Ambrosioni, Jhon Rojas, Alexy Inciarte, Berta Torres, Alex Soriano, José Antonio Martínez, Josep Mensa, Marta Hernández-Meneses, Laura Morata, Mariana Chumbita, Pau Alcubilla, Veronica Rico, Daiana Aguero, Nicole García-Pouton, Laia Albiach, Fernanda Meira, Lorena De la Mora, laura Linares, Irene Macaya, Montse Laguno, Angela Ramos, Estela Moreno-García, Antonio Moreno, Montse Sola, Lorna Leal, Manuel Torres |
| المصدر: |
BMJ Open, Vol 11, Iss 8 (2021) |
| بيانات النشر: |
BMJ Publishing Group, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Medicine |
| مصطلحات موضوعية: |
Medicine |
| الوصف: |
Importance Identifying undetected clinical signs is imperative in the prevention of SARS-CoV-2.Objective To establish the prevalence of clinical gustatory and olfactory dysfunctions in patients with COVID-19 pneumonia. Clinical outcomes and recovery rates associated with gustatory and olfactory dysfunctions were also assessed.Design A prospective study was performed in 80 patients admitted to Hospital Clínic of Barcelona (Spain) for COVID-19 pneumonia. Patients were re-evaluated in the ward daily until discharge. Gustatory and olfactory dysfunction symptoms were retrospectively collected from emergency room (ER) charts after first assessments. Follow-up was performed in telemedicine consultation.Setting The single-centre study was performed in a hospitalisation ward at a university hospital.Participants Consecutive patients meeting hospitalisation criteria for COVID-19 pneumonia were eligible. Study exclusion criteria were patients who could not speak, had previous gustatory and olfactory dysfunctions or whose PCR tests for SARS-CoV-19 were negative.Interventions Systematic assessment of gustatory and olfactory symptoms with standardised questions.Outcome(s) Prevalence of gustatory and olfactory dysfunctions in patients with COVID-19 pneumonia.Results Of the 80 study subjects, 62.5% were male and the median age was 57 years. Half of the cohort (n=40) presented with comorbidities. The prevalence of chemosensitive disorder was 73.8% (n=59) (95% CI: 63.8 to 83.8), although self-reported symptoms were recorded in only 26.3% (n=21) of patients in the ER. Gustatory and olfactory dysfunctions were observed in 58.8% (n=47) and 55% (n=44) of cases, respectively. They were also the first symptoms in 25% (n=20) of patients. Anosmia was associated with ageusia, OR: 7, 95% CI: 2.3 to 21.8, p=0.001). No differences in clinical outcomes were observed when patients with and without gustatory and olfactory dysfunctions were compared. Recovery rates were 20% (n=10) and 85% (n=42) at days 7 and 45, respectively.Conclusion The prevalence of gustatory and olfactory dysfunctions in COVID-19 pneumonia was much higher than in self-report. Presence of gustatory and olfactory dysfunctions was not a predictor of clinical outcomes. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2044-6055 |
| Relation: |
https://bmjopen.bmj.com/content/11/8/e040775.full; https://doaj.org/toc/2044-6055 |
| DOI: |
10.1136/bmjopen-2020-040775 |
| URL الوصول: |
https://doaj.org/article/7be9b6443cbb4f6ea985ac53fac037ec |
| رقم الانضمام: |
edsdoj.7be9b6443cbb4f6ea985ac53fac037ec |
| قاعدة البيانات: |
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