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Real‐world risk of cardiovascular diseases in patients with type 2 diabetes associated with sodium–glucose cotransporter 2 inhibitors in comparison with metformin: A propensity score‐matched model analysis in Japan

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العنوان: Real‐world risk of cardiovascular diseases in patients with type 2 diabetes associated with sodium–glucose cotransporter 2 inhibitors in comparison with metformin: A propensity score‐matched model analysis in Japan
المؤلفون: Takeshi Horii, Yoichi Oikawa, Akira Shimada, Kiyoshi Mihara
المصدر: Journal of Diabetes Investigation, Vol 14, Iss 11, Pp 1262-1267 (2023)
بيانات النشر: Wiley, 2023.
سنة النشر: 2023
المجموعة: LCC:Diseases of the endocrine glands. Clinical endocrinology
مصطلحات موضوعية: Cardiovascular disease, Metformin, Sodium–glucose cotransporter 2 inhibitors, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
الوصف: Abstract We aimed to compare the effects of cardiovascular disease risk in Japanese patients with type 2 diabetes on sodium–glucose cotransporter 2 inhibitors (SGLT2Is) or metformin. This retrospective, real‐world cohort study was carried out using a claims database and propensity score matching; 58,402 eligible patients (29,201 per group) were included. The outcomes included nonfatal myocardial infarction, angina pectoris, nonfatal stroke, hospitalization for heart failure and composite end‐points. The hazard ratio (HR) for the composite end‐point was 0.79, which was lower for SGLT2Is than for metformin. For male patients (HR 0.76), patients aged
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2040-1124
2040-1116
Relation: https://doaj.org/toc/2040-1116; https://doaj.org/toc/2040-1124
DOI: 10.1111/jdi.14062
URL الوصول: https://doaj.org/article/7a267bd1833245f0b4fc512e0a9fc97d
رقم الانضمام: edsdoj.7a267bd1833245f0b4fc512e0a9fc97d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20401124
20401116
DOI:10.1111/jdi.14062