Academic Journal
Study on thedistribution of high titer neutralizing antibody against human cytomegalovirus in plasma donors
| العنوان: | Study on thedistribution of high titer neutralizing antibody against human cytomegalovirus in plasma donors |
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| المؤلفون: | Junying SHEN, Wenjuan GE, Xiaoqing LI, Lele YANG, Yanyan GONG, Jie MA |
| المصدر: | Zhongguo shuxue zazhi, Vol 35, Iss 1, Pp 43-46 (2022) |
| بيانات النشر: | Institute of Blood Transfusion of Chinese Academy of Medical Sciences, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the blood and blood-forming organs LCC:Medicine |
| مصطلحات موضوعية: | human cytomegalovirus, neutralizing antibody, anti-hcmv screening, anti-hcmv, plasma donors, raw plasma, Diseases of the blood and blood-forming organs, RC633-647.5, Medicine |
| الوصف: | Objective To investigate the distribution of plasma donors with high titer neutralizing antibodies against human cytomegalovirus (HCMV) in the general plasma donor population. Methods 920 plasma samples of Taibang were tested in April 2014 to investigate the distribution of anti-HCMV neutralizing antibodies. After further testing of mixed plasma, the threshold for screening plasma was determined. From October 2019 to May 2020, neutralizing anti-HCMV in 40 078 plasma samples from 11 plasma stations in Shandong province were screened by the microcytopathic method (modified high-flux neutralization test method). The proportion of neutralizing anti-HCMV enriched in high titer and the distribution in the donor population were analyzed by SPSS 26 and Minitab19 analysis software. Results Among 920 samples, 73.26%, 0.43%, and 8.69% of them had neutralization titer |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Chinese |
| تدمد: | 1004-549X 1004-549x |
| Relation: | https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2022.01.012&lang=en; https://doaj.org/toc/1004-549X |
| DOI: | 10.13303/j.cjbt.issn.1004-549x.2022.01.012&lang=en |
| DOI: | 10.13303/j.cjbt.issn.1004-549x.2022.01.012 |
| URL الوصول: | https://doaj.org/article/793ca5912ef448198981a89c64faa6e0 |
| رقم الانضمام: | edsdoj.793ca5912ef448198981a89c64faa6e0 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 1004549X 1004549x |
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| DOI: | 10.13303/j.cjbt.issn.1004-549x.2022.01.012&lang=en |