Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1) disease.

التفاصيل البيبلوغرافية
العنوان:	Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1) disease.
المؤلفون:	Oliver W Morgan, Anna Bramley, Ashley Fowlkes, David S Freedman, Thomas H Taylor, Paul Gargiullo, Brook Belay, Seema Jain, Chad Cox, Laurie Kamimoto, Anthony Fiore, Lyn Finelli, Sonja J Olsen, Alicia M Fry
المصدر:	PLoS ONE, Vol 5, Iss 3, p e9694 (2010)
بيانات النشر:	Public Library of Science (PLoS), 2010.
سنة النشر:	2010
المجموعة:	LCC:Medicine LCC:Science
مصطلحات موضوعية:	Medicine, Science
الوصف:	BACKGROUND: Severe illness due to 2009 pandemic A(H1N1) infection has been reported among persons who are obese or morbidly obese. We assessed whether obesity is a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1), independent of chronic medical conditions considered by the Advisory Committee on Immunization Practices (ACIP) to increase the risk of influenza-related complications. METHODOLOGY/PRINCIPAL FINDINGS: We used a case-cohort design to compare cases of hospitalizations and deaths from 2009 pandemic A(H1N1) influenza occurring between April-July, 2009, with a cohort of the U.S. population estimated from the 2003-2006 National Health and Nutrition Examination Survey (NHANES); pregnant women and children or=20 year olds, hospitalization was associated with being morbidly obese (BMI>or=40) for individuals with ACIP-recognized chronic conditions (OR = 4.9, 95% CI 2.4-9.9) and without ACIP-recognized chronic conditions (OR = 4.7, 95%CI 1.3-17.2). Among 2-19 year olds, hospitalization was associated with being underweight (BMIor=20 years without ACIP-recognized chronic medical conditions death was associated with obesity (OR = 3.1, 95%CI: 1.5-6.6) and morbid obesity (OR = 7.6, 95%CI 2.1-27.9). CONCLUSIONS/SIGNIFICANCE: Our findings support observations that morbid obesity may be associated with hospitalization and possibly death due to 2009 pandemic H1N1 infection. These complications could be prevented by early antiviral therapy and vaccination.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	1932-6203
Relation:	http://europepmc.org/articles/PMC2837749?pdf=render; https://doaj.org/toc/1932-6203
DOI:	10.1371/journal.pone.0009694
URL الوصول:	https://doaj.org/article/7798cf0e2bbb405e8305ed1c2c8920d9
رقم الانضمام:	edsdoj.7798cf0e2bbb405e8305ed1c2c8920d9
قاعدة البيانات:	Directory of Open Access Journals

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الوصف
تدمد:	19326203
DOI:	10.1371/journal.pone.0009694