Academic Journal
Significant increased isolation of Escherichia coli in Iranian women with endometriosis: a case control – study
| العنوان: | Significant increased isolation of Escherichia coli in Iranian women with endometriosis: a case control – study |
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| المؤلفون: | Zohreh Tavana, Elham Askary, Mohammad Motamedi Far, Faranak Fatehpoor, Saeedeh Frooghinia, Alimohammad Keshtvarz Hesam Abadi, Kefayat Chamanara, Saeed Alborzi |
| المصدر: | BMC Women's Health, Vol 24, Iss 1, Pp 1-7 (2024) |
| بيانات النشر: | BMC, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Gynecology and obstetrics LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Endometriosis, Endometritis, Culture, Escherichia coli, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270 |
| الوصف: | Abstract Background The role of bacterial contamination in the development and progression of endometriosis lesions is currently a hot topic for gynecologists. In this study, we decided to compare the endometrial cultures of women affected by endometriosis with those of non-endometriotic women, focusing on specific microbial pathogens. Material and method In this cross-sectional case-control study, 30 women with endometriosis in stages 4 of the disease whose endometriosis was confirmed based on clinical, ultrasound, and histopathological findings, and 30 women without endometriosis who were candidates for surgery due to benign uterine diseases with regular menstrual cycle, underwent endometrial biopsy with Novak Kort in sterile conditions before starting their operation, and the results of their endometrial culture were analyzed and compared. Results Results of the study indicate that there were no significant differences in terms of age, BMI, smoking, education level, place of residency, use of the intrauterine device, or vaginal douche, and age of menarche between the case and control groups. The only demographic difference observed was in parity, where the control group had a significantly higher parity than the case group (P = 0.001). Out of the 60 cultures, only 15 samples were positive in the endometriosis group, and E. coli was the most prevalent species, with 10 (33.3%) samples testing positive for it. Klebsiella spp. and Enterobacteria spp. were also detected in 3 (10.0%) and 2 (6.7%) samples, respectively. The comparison between the two groups showed that only E. coli had a significant association with the presence of endometriosis (P = 0.001). There was no significant relationship between the location of endometriosis in the pelvic cavity and culture results. It was observed that parity among the E. coli negative group was significantly higher compared to the E. coli positive group (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1472-6874 |
| Relation: | https://doaj.org/toc/1472-6874 |
| DOI: | 10.1186/s12905-024-03229-2 |
| URL الوصول: | https://doaj.org/article/776ed91e810640f89e83052ef2e28202 |
| رقم الانضمام: | edsdoj.776ed91e810640f89e83052ef2e28202 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14726874 |
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| DOI: | 10.1186/s12905-024-03229-2 |